Results 171 to 180 of about 1,917,089 (269)

Predictors of palliative care attitudes among US patients with cancer and survivors: ideology, personality, world beliefs. [PDF]

BMJ Support Palliat Care
Kerry N, Perry LM, Clifton JDW.
europepmc   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Does vitamin D status impact mortality from SARS-CoV-2 infection?

Medicine in Drug Discovery, 2020
Paul E. Marik, Pierre Kory, Joseph Varon
doaj   +1 more source

Factors associated with the life-space assessment in community-dwelling older adults requiring support. [PDF]

J Phys Ther Sci
Hosaka K, Uchinoura M, Otao H, Shibata H.   +3 more
europepmc   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Assessing outcomes : a social psychological interpretation of life course trajectories for young people leaving care

This study explores the experiences of young people who have been 'looked after' during the transitional period in which they leave 'care', moving on to live independently.
Horrocks, Christine
core  

Psychosocial pathways linking type D personality traits to quality of life in patients with permanent intestinal stomas: a cross-sectional structural equation modeling study. [PDF]

Front Med (Lausanne)
Tan C, Zhang H, Jiang Y, Zhang Y, Yu M.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Outcome measurement tools in pediatric oncology palliative care: a scoping review of domains, validation and contextual relevance. [PDF]

BJC Rep
Verma V, Ghoshal A, Mathew M, D H, Sanian A, S Rao K, Bhat K V, Salins N.   +7 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source