Results 51 to 60 of about 1,917,089 (269)

Evidence-based planning and costing palliative care services for children : novel multi-method epidemiological and economic exemplar [PDF]

open access: yes, 2013
Background: Children’s palliative care is a relatively new clinical specialty. Its nature is multi-dimensional and its delivery necessarily multi-professional.
Lucie Hobson   +36 more
core   +1 more source

Prognostic accuracy of oxygen debt for mortality in patients undergoing venoarterial extracorporeal membrane oxygenation therapy: a retrospective cohort study

open access: yesFrontiers in Medicine
BackgroundCardiogenic shock is associated with high mortality. Prognostic scales, such as Sequential Organ Failure Assessment (SOFA), Acute Physiology and Chronic Health Evaluation II (APACHE II), and Survival After Venoarterial ECMO (SAVE), have been ...
Michel Perez-Garzon   +9 more
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

The functional landscape of critical care: a nationwide study of volume, capability, and institutional variation in South Korea [PDF]

open access: yesAcute and Critical Care
Background In Korea, intensive care units (ICUs) are defined mainly by administrative categories, which do not reflect functional capability. This study examined the relationship between hospital capacity and functional performance by analyzing ...
Ho Kyung Sung   +5 more
doaj   +1 more source

The Mediator Role of Meaning in Life in the Life Quality of Patients With Chronic Heart Failure

open access: yesAsian Nursing Research, 2023
Summary: Purpose: Heart failure (HF) is a highly recurrent disease with a high sudden death rate and a substantial influence on disease-related quality of life (QOL). Social support, symptom distress, care needs, and meaning in life all have significant
Min-Hui Liu, Chao-Hung Wang, Ai-Fu Chiou
doaj   +1 more source

Heterogeneity in the Global Practice of Central Nervous System Staging in Pediatric Acute Lymphoblastic Leukemia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási   +14 more
wiley   +1 more source

Sharing the care: The key working experiences of professionals and parents of life limited children.

open access: yes, 2014
Aims: To explore the lived experience of caring and care planning for a child with a life-limiting condition (LLC). Method: Using van Manen’s conceptualisation of hermeneutic phenomenology, three focus groups were conducted with 21 paediatric ...
King, Nigel, Rodriguez, Alison
core   +1 more source

Thrombocytopenia in critically ill trauma patients is associated with the pattern and duration of postinjury organ dysfunction

open access: yesResearch and Practice in Thrombosis and Haemostasis
Background: Although significant thrombocytopenia is not a common feature of trauma patients in the first hours after injury, little is known about how severe trauma affects platelet count trajectories beyond the initial resuscitation phase and whether ...
Andrea Rossetto   +6 more
doaj   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

End-of-life care and dementia

open access: yes, 2006
In the UK, research continues to confirm that people with certain chronic illnesses, such as chronic lung disease and cardiac failure, represent the ‘disadvantaged dying’ compared to those with terminal cancer.
Keady, John   +5 more
core   +1 more source

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