Results 51 to 60 of about 5,141,848 (309)

Factor structure and construct validity of the Adult Social Care Outcomes Toolkit for Carers (ASCOT-Carer) [PDF]

, 2015
Background: The ASCOT-Carer is a self-report instrument designed to measure social care-related quality of life (SCRQoL). This article presents the psychometric testing and validation of the ASCOT-Carer four response-level interview (INT4) in a sample of
A Bowling, A Camden, AK Ekwall, Ann P. Netten, AP Netten, B Robinson, B Schoenmakers, C Cohen, C Mockford, C Quinn, C Quinn, CL White, D Potoglou, Department of Health, Department of Health, Department of Health, Department of Health, DL Streiner, E Courtin, E Moniz-Cook, ETP Heuvel Van den, G Willis, GJ Molloy, H Al-Janabi, H Al-Janabi, J Cortina, J Harden, J Malley, JE Gaugler, JN Morris, Julien E. Forder, Juliette N. Malley, K Harvey, L Cronbach, L Cronbach, L Hu, L Kitrungrote, LP McKeown, M Evans, M Hughes, M Naiditch, MI Zegwaard, N Greenwood, OECD, PL Hudson, R Brooks, R Romero-Moreno, R Schulz, R Schulz, RB Kline, RD Hays, S Bridges, S Rand, S Sorensen, SI Reed, Stacey E. Rand, The EuroQol Group, U Stenberg   +57 more
core   +1 more source

Personalized Selumetinib Dosing in Pediatric Neurofibromatosis Type 1: Insights From a Pilot Therapeutic Drug Monitoring Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Objective To evaluate selumetinib exposure using therapeutic drug monitoring (TDM) in pediatric patients with neurofibromatosis type 1 (NF1) and plexiform neurofibromas (PN), assess interpatient pharmacokinetic variability, and explore the relationship between drug exposure, clinical response, and adverse effects.
Janka Kovács, Zoltán Köllő, Balázs Gellért Karvaly, Mahmoud Obeidat, Rita Nagy, Péter Hegyi, Brigitta Teutsch, Eszter Tuboly, Miklós Garami   +8 more
wiley   +1 more source

ECMO‐Assisted Da Vinci Robotic Surgery for Pheochromocytoma‐Induced Acute Catecholamine Cardiomyopathy: A Case Report

Clinical Case Reports
Pheochromocytoma, an uncommon neuroendocrine neoplasm, has the potential to precipitate acute catecholamine cardiomyopathy (ACIC), a perilous condition characterized by cardiogenic shock and the failure of multiple organ systems.
Qi Wang, Jiayan Xin, Xiaoqiong Cui, Liya Hu, Meng Ning, Wenqing Gao, Yingwu Liu   +6 more
doaj   +1 more source

Adherence to Protocol Recommendations for Children With Wilms Tumour in Two Consecutive Studies in the United Kingdom and Ireland—Does Variation Matter?

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background and Aims Wilms tumour (WT) has excellent event‐free and overall survival (OS). However, small differences exist between countries participating in the same international study. This led us to examine variation in adherence to protocol recommendations as a potential contributing factor.
Suzanne Tugnait, R. Al‐Saadi, A. Lopez‐Cortes, K. Dzhuma, M. Oostveen, J. Brok, S. Irtan, M. Weeks, J. Bate, S. Baker, R. Williams, M. Powis, D. Saunders, O. Olsen, T. Watson, S. Shelmerdine, S. Vaidya, L. Howell, C. Duncan, G. M. Vujanic, C. Stiller, G. P. Balchin, T. Chowdhury, K. Pritchard‐Jones   +23 more
wiley   +1 more source

Sirolimus for Extracranial Arteriovenous Malformations: A Scoping Review of the Evidence in Syndromic and Non‐Syndromic Cases

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson, Ingrid Winship, Gary Hammerschlag, Laura Scardamaglia   +3 more
wiley   +1 more source

Provider Perspectives on the Influence of Family on Nursing Home Resident Transfers to the Emergency Department: Crises at the End of Life. [PDF]

, 2015
Background. Nursing home (NH) residents often experience burdensome and unnecessary care transitions, especially towards the end of life. This paper explores provider perspectives on the role that families play in the decision to transfer NH residents to
Bui, Nhat, Halifax, Elizabeth, Harrington, Charlene, Lee, Sei J, Ritchie, Christine, Shim, Janet, Stephens, Caroline   +6 more
core   +3 more sources

Preferences of Pediatric Patients and Their Caregivers for Chemotherapy‐Induced Nausea and Vomiting Control Endpoints: A Mixed Methods Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Although not always achieved, complete chemotherapy‐induced nausea and vomiting (CINV) control is the conventional goal of CINV prophylaxis. In this two‐center, mixed‐methods study, we sought to understand the preferences of adolescent patients and family caregivers for CINV control endpoints.
Haley Newman, Tadi Hondonga, Alison Berry, Caitlin Elgarten, Jason Freedman, Katelyn Oranges, Sara McDonough, Caroline Diorio, L. Lee Dupuis   +8 more
wiley   +1 more source

The impact of patients' chronic disease on family quality of life : an experience from 26 specialties [PDF]

, 2013
BACKGROUND: Previous studies have assessed family quality of life in individual disease areas and specialties. The aim of this study was to investigate the impact of disease on family members of patients over a wide range of specialties and identify key ...
Basra, Mohammad Khurshid Azam, Finlay, Andrew Yule, Golics, Catherine Jane, Salek, M Sam   +3 more
core   +3 more sources

Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul, Jatuporn Sujjitjoon, Pa‐thai Yenchitsomanus, Kridtin Jarutatsanangkoon, Ng Wei Loon, Kleebsabai Sanpakit, Jassada Buaboonnam, Chayamon Takpradit, Pornpimon Yuti, Nunghathai Sawasdee, Piriya Luangwattananun, Siripakorn Sangkitporn, Arnan Limmahachai, La‐ongsri Atchaneeyasakul   +13 more
wiley   +1 more source

Experiencing Breast Cancer Confronts Death but Reconciles with Life: A Qualitative Study Using Grounded Theory Methodology

Iatreia
Introduction: Breast cancer is the most common oncological diagnosis in women, and experiencing it generates physical, psychological, and social demands.
Ríos-Córdoba, Diana Carolina, Figueroa-Cuesta, Juan David, Alzate-Vanegas, Sandra Isabel, Contreras-Pérez, Daniel Fernando, Yepes-Delgado, Carlos Enrique   +4 more
doaj   +1 more source