Results 81 to 90 of about 21,698,107 (285)

Skylab astronaut life support assembly [PDF]

open access: yes, 1972
A comparative study was performed to define an optimum portable life support system for suited operations inside and outside the Skylab Program. Emphasis was placed on utilization of qualified equipment, modified versions of qualified equipment, and new ...
Brown, J. T.
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

IMPROVEMENT OF LIFE SUPPORT SYSTEMS OF PASSENGER ROLLING STOCK: PATENT REVIEW

open access: yesNauka ta progres transportu, 2018
Purpose. Inventors and researchers of the world are focused on improvements of basic life support systems including provision of quality microclimate parameters in a car of the rolling stock.
S. R. Kolesnykov
doaj   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Hybrid control systems

open access: yes, 2004
Most practical control systems involve both analogue and logic components. Hybrid control system is a generic term for such systems, where the continuous and the discrete dynamics are interacting.
Johansson, Karl Henrik
core   +2 more sources

Integrating life support systems into 3D-printed extra-terrestrial habitat envelopes

open access: yesFrontiers in Space Technologies
When designing and constructing habitats on Mars, one of the main challenges is the extreme environment, which lacks a breathable atmosphere and atmospheric pressure, and is characterized by extreme temperature fluctuations and high radiation levels. The
A. J. Hidding, H. H. Bier, F. Alsaggaf
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Customizing GPT for natural language dialogue interface in database access

open access: yesGenomics & Informatics
The paper presents Anatomy3DExplorer, a customized ChatGPT designed as a natural language dialogue interface for exploring 3D models of anatomical structures.
Jin-Dong Kim, Kousaku Okubo
doaj   +1 more source

Affective Stimuli for an Auditory P300 Brain-Computer Interface

open access: yesFrontiers in Neuroscience, 2017
Gaze-independent brain computer interfaces (BCIs) are a potential communication tool for persons with paralysis. This study applies affective auditory stimuli to investigate their effects using a P300 BCI.
Akinari Onishi   +8 more
doaj   +1 more source

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