Results 121 to 130 of about 13,071,015 (306)

The crossover between life expectancies at birth and at age one: The imbalance in the life table [PDF]

open access: yes
The single most used demographic measure to describe population health is life expectancy at birth, but life expectancies at ages other than zero are also used in the study of human longevity.
Stan Becker, Vladimir Canudas-Romo
core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Life table parameters of grape phylloxera treated by β-ecdysterone three lethal concentrations.

open access: yes, 2016
Life table parameters of grape phylloxera treated by β-ecdysterone three lethal concentrations.
Khalid Hussain Dhiloo (771738)   +6 more
core   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Some Demographic Consequences of Revising the Definition of 'Old' to Reflect Future Changes in Life Table Probabilities [PDF]

open access: yes
Sixty-five has long been used to define the beginning of 'old age'. Yet it is clear that the definition is arbitrary, and with continuing reductions in mortality and morbidity rates it will become increasingly inappropriate as time passes.
Byron G. Spencer, Frank T. Denton
core   +2 more sources

Life-table representations of family dynamics in Sweden, Hungary, and 14 other FFS countries [PDF]

open access: yes
In this study, we present a system of descriptions of family-demographic behavior in developed countries. We use life-table techniques in order to describe the experience of men, of women, and of children in processes related to family formation and ...
Gunnar Andersson, Dimiter Philipov
core  

Life table parameters of black soldier fly reared on two different diets at constant temperatures.

open access: yes, 2018
Life table parameters of black soldier fly reared on two different diets at constant temperatures.
Samira A. Mohamed (307649)   +10 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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