Results 101 to 110 of about 3,209,297 (289)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A model for geographical variation in health and total life expectancy
Demographic Research, 2006 This paper develops a joint approach to life and health expectancy based on 2001 UK Census data for limiting long term illness and general health status, and on registered death occurrences in 2001.
Peter Congdon
doaj
Mortality tempo versus removal of causes of mortality [PDF]
We propose an alternative way of dealing with mortality tempo. Bongaarts and Feeney have developed a model that assumes a fixed delay postponing each death.
Hervé Le Bras
core
Measuring the Rectangularization of Life Tables Using the Gompertz Distribution [PDF]
, 2010 The rectangularization of life tables is defined as a trend towards a more rectangular shape of the survival curve due to increased survival and concentration of deaths around the mean age at death.
Pflaumer, Peter
core
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Area-based social inequalities in adult mortality: construction of French deprivation-specific life tables for the period 2016-2018. [PDF]
Front Public Health, 2023 Merville O +5 more
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Croatian Review of Economic, Business and Social Statistics, 2019 This article provides an upgraded model for actuarial projection of the dependency ratio of the pension fund in the Republic of Srpska. The nonexistence of complete upto-date life tables presents a huge problem of the pension system and life insurance ...
Bošnjak Nikolina, Prorok Vesna
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Life tables of annual life expectancy and mortality for companion dogs in the United Kingdom. [PDF]
Sci Rep, 2022 Teng KT +4 more
europepmc +1 more source