Results 131 to 140 of about 1,150,597 (304)

Intermittent Fasting Restores Cardiac Lipid Homeostasis in Diabetic Cardiomyopathy in Association With Akkermansia Muciniphila and 1‐methyl‐L‐histidine

Advanced Science, EarlyView.
Intermittent fasting reshapes the gut microbiota in diabetic cardiomyopathy, restoring Akkermansia muciniphila and the microbiota‐associated metabolite 1‐methyl‐L‐histidine. This shift is linked to improved cardiac lipid homeostasis, reduced lipid peroxidation, and attenuated myocardial injury, highlighting a gut microbiota–metabolite–lipid axis in ...
Kaiyuan Jiang, Fen Xiong, Yiwen Peng, Lingfei Meng, Xinran Wang, Yingruo Xu, Tian Tang, Hongchang Gao   +7 more
wiley   +1 more source

Motivation and decision-making in referrals to lifestyle interventions by primary care general practitioners [PDF]

, 2017
Poster presentation. There still is little empirical evidence on factors that influence GPs’ referral behavior to lifestyle interventions. The aim was to explore 1) GPs´ motivation to refer to lifestyle interventions and to investigate the association ...
Dijkstra, Arie, Lemmink, Koen, Baarveld, Frank, Bouma, Adrie, van Wilgen, C. Paul, Diercks, Ron   +5 more
core  

Membrane‐Active Peptide Protects Against Inflammation by Targeting NLRP3 Activation at the Trans‐Golgi Network

Advanced Science, EarlyView.
The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt, Nico Kirsch, Aileen Kerfin, Lars P. Lunding, Dominic Ferber, Hannes Buthmann, Ilka Schreier, Carlotta Bosio, Ann‐Kathrin Dobbelstein, Anna Klawonn, Rebecca C. Coll, Lena Bauernhofer, Sandro Keller, Matthias Geyer, Michael Wegmann, Andra B. Schromm, Günther Weindl   +16 more
wiley   +1 more source

Preclinical atherosclerosis and prediabetes: a cross-sectional metabolic assessment in apparently healthy population

Cardiovascular Diabetology
Introduction Prediabetes and preclinical atherosclerosis are interrelated conditions contributing to cardiovascular risk, even in apparently healthy individuals.
Natalia Zieleniewska, Jacek Jamiołkowski, Marcin Kondraciuk, Michal Ciborowski, Katarzyna Ptaszyńska, Małgorzata Chlabicz, Marlena Dubatówka, Urszula Roszkowska, Irina Kowalska, Karol Kamiński   +9 more
doaj   +1 more source

Microprotein MP104 Promotes Malignant Progression of Colorectal Cancer Through Regulating Protein Translation

Advanced Science, EarlyView.
A previously unrecognized microprotein, MP104, encoded by ZEB1‐AS1, emerges as a critical driver of colorectal cancer progression. MP104 links ubiquitin‐mediated protein degradation with translational reprogramming via the UBE2O–AMPKα2–mTOR–EIF4B axis, revealing an unrecognized layer of oncogenic regulation.
Fang Chen, Miao Wang, Hongmei Yong, Jin Ding, Shiping Xu, Qirui Ge, Yan Wang, Lei Zhang, Qianqian Xiao, Benli Li, Li Lin, Sufang Chu, Qianqing Wang, Jin Bai, Pingfu Hou   +14 more
wiley   +1 more source

Separate associations of waist and hip circumference with lifestyle factors

, 1998
OBJECTIVE: To study the associations of lifestyle factors with waist circumference 'Action Levels', hip circumference and body mass index. DESIGN: Cross-sectional study in a random sample of 5887 men and 7018 women aged 20-59 years, selected from the ...
Han, T.S., Bijnen, F C, Lean, M.E.J., Seidell, J C; id_orcid, Seidell, J C   +4 more
core   +1 more source

scTIDE: Deciphering Critical Transitions Through Cell‐Perturbed Manifold Graphs and Optimal Transport Conditional Flow Matching

Advanced Science, EarlyView.
scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong, Bowen Niu, Yongbo Yu, Shiyang Nie, Xuerong Gu, Pei Chen, Rui Liu   +6 more
wiley   +1 more source

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

Advanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma, Yaqing Chen, Yiwen Gao, Xueting Hu, Qun Yang, Yucheng Liu, Peiyong Xin, Jijun Yan, Jinfang Chu, Lei Li, Zhixi Tian, Bo Ren   +11 more
wiley   +1 more source

The impact of various forms of non-alcoholic beverage taxation on sales of non-alcoholic beverages and sugar in the Netherlands: a modelling study

BMC Public Health
Background In January 2024, the flat consumption tax on non-alcoholic beverages in the Netherlands was increased from €8.83 per 100 l to €26.13 per 100 l. In various countries tiered taxes have been implemented.
Michelle Eykelenboom, Marije Oosterhoff, Ivon E. J. Milder, Anoukh van Giessen   +3 more
doaj   +1 more source

Green Lifestyle Journalism

This chapter outlines the scope and meanings of green lifestyle journalism where environmentalism, sustainability, and individual everyday life practices are explored.
Craig, Geoff
core   +1 more source