Results 81 to 90 of about 1,150,597 (304)

Safety and Efficacy of GLP‐1 Receptor Agonists in Adults With Epilepsy, Obesity, and Type 2 Diabetes

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Managing obesity in patients with epilepsy is complicated by the weight‐gaining properties of essential antiseizure medications (ASMs) such as valproate and pregabalin. We evaluated the safety and efficacy of initiating glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) in this population.
Hyoshin Son   +3 more
wiley   +1 more source

Clinical characteristics of patients with autosomal dominant polycystic kidney disease and risk factors for kidney function decline: a single-center study

open access: yesRenal Replacement Therapy
Background Autosomal dominant polycystic kidney disease (ADPKD) leads to end-stage renal disease (ESRD) in approximately half of all patients with ADPKD by their sixth decade of life.
Masato Minami   +16 more
doaj   +1 more source

Preoperative classification of submucosal fibrosis in colorectal laterally spreading tumors by endoscopic ultrasonography

open access: yesEndoscopy International Open, 2015
Background and study aims: Although endoscopic submucosal dissection (ESD) is an established therapy for colon neoplasms including laterally spreading tumors (LSTs), its application to advanced fibrotic lesions is very difficult owing to the thin walls ...
Tomoaki Makino   +13 more
doaj   +1 more source

Analysis of the dietary habits and health and lifestyle characteristics of Trafford Borough residents [PDF]

open access: yes, 2008
Aim: To investigate the health and lifestyle characteristics of a representative sample of Trafford Borough residents (n = 316), using data from a Health and Lifestyle questionnaire, with emphasis on eating behaviour and dietary habits.
Charnley, Georgina
core   +2 more sources

Autoimmune Comorbidities as Modifiers of Phenotypic Heterogeneity in Facioscapulohumeral Dystrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral dystrophy type 1 (FSHD1) shows clinical heterogeneity that is only partly explained by D4Z4 repeat unit (RU) size. Although immune and inflammatory mechanisms may contribute to disease variability, the prevalence and clinical impact of autoimmune diseases in FSHD remain unclear.
Jonathan Pini   +9 more
wiley   +1 more source

Impact of blood flow restriction training timing: Does exercising at dusk or dawn enhance response?

open access: yesPhysiological Reports
Data suggest that skeletal muscles have an internal clock that dictates training‐related adaptations, which could generate different health benefits in response to exercise timing. However, limited data exist on the impact of blood flow restriction (BFR)
L. E. Peskett   +6 more
doaj   +1 more source

Healthy lifestyle interventions : a systematic review from a realist perspective [PDF]

open access: yes, 2014
This thesis is a systematic review using realist methodology. It emerged out of an original protocol that proposed an exploration of the barriers to a healthy lifestyle in poorer peri-urban communities.
Voss, Miranda
core   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai   +13 more
wiley   +1 more source

Dilation Device Use and Concomitant Antegrade Stenting are Associated With Procedure‐related Early Adverse Events After Endoscopic Ultrasound‐guided Hepaticogastrostomy: A Retrospective Multicenter Study

open access: yesDEN Open
Objectives Endoscopic ultrasound‐guided hepaticogastrostomy (EUS‐HGS) is useful in cases of endoscopic retrograde cholangiopancreatography failure. However, the procedure has a high incidence of procedure‐related early adverse events (PRAEs).
Shinichi Hashimoto   +19 more
doaj   +1 more source

Osteoporosis and Lifestyle

open access: yesJournal of Nutritional Science and Vitaminology, 2015
Skeletal tissue is formed during the first two decades of life; then a constant bone mass is maintained until 40 y of age. In the case of women, the bone mass is rapidly reduced at menopause at around 50 y of age. After that, bone mass slowly decreases in both men and women who have passed the 70-y-old mark.
openaire   +3 more sources

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