Results 131 to 140 of about 238,879 (302)
Advanced Science, EarlyView.scTIDE identifies single‐cell tipping points by combining manifold‐based graph representations with optimal‐transport conditional flow matching, which preserves intrinsic topology and models distributional dynamics. It supports critical‐transition detection at individual‐cell resolution, prediction of unseen cells, and dimensionality reduction and ...
Jiayuan Zhong +6 more
wiley +1 more source
Marketing sustainable lifestyles
Marketing sustainable lifestyles requires a rapid reorientation away from perpetuating unsustainable behaviours and lifestyles with far-reaching implications for people and the planet. This chapter thus sets out to circumscribe how the enormous potential
Mont, O., Isham, A., Elf, P.
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Advanced Science, EarlyView.A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma +11 more
wiley +1 more source
A Panel of Circulating Exosomal sncRNAs Associated With Lung Cancer Risk up to 10 Years in Advance
Advanced Science, EarlyView.Lung cancer is often diagnosed too late, and current screening overlooks many people at risk. In a long‐term study of smokers, a panel of small non‐coding RNAs carried in blood exosomes signals elevated lung cancer risk up to ten years before diagnosis, pointing toward a blood‐based tool for earlier risk detection.
Zhuokun Feng +12 more
wiley +1 more source
BMC Public HealthBackground Eating disorders (ED) most often develop during adolescence and young adulthood. Therefore, university is deemed a period of risk due to increased academic demands and uncertainty about the future. Despite the high prevalence of ED among young
Maria Antònia Amengual-Llofriu +2 more
doaj +1 more source
Advanced Science, EarlyView.Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon +6 more
wiley +1 more source
Advanced Science, EarlyView.Our study identifies an Hnf4a‐driven super‐enhancer of hepatic Ahcy that mediates the protective effects of intermittent fasting against MASLD. Disruption of the Ahcy super‐enhancer reduces Ahcy expression and exacerbates lipid accumulation. This pathway prevents aberrant promoter hypermethylation by maintaining the SAM/SAH balance, as exemplified by ...
Huafeng Chen +6 more
wiley +1 more source
Enlarged carbon footprint inequality considering household time use pattern
Environmental Research LettersExamining household carbon emissions through a supply chain perspective reveals the climate impact of consumption behaviors and variations across societal structures and features. Despite the evident and expanding environmental inequality, strategies for
Yin Long +4 more
doaj +1 more source
Positive sexual health: an ethnographic exploration of social and cultural factors affecting sexual lifestyles and relationships of Nepalese young people in the UK [PDF]
, 2017 This PhD is an interdisciplinary research project in the field of public health, youth studies, sociology and cultural studies about the sexual lives of 16 young Nepalese aged 16-24 living in London. The research uses ethnography and biography to explore
Sah, R.
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