Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli +5 more
wiley +1 more source
Valuation of TMF Lifetime Calculation Methods and their Limitations of Usability
Cyclic loading of metallic engineering components at constant elevated or fluctuating temperature causes a complex evolution of damage which can hardly be described. At the same time the thermal expansion is restricted in some regions, due to the complex
H. Köberl +2 more
core +1 more source
Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi +8 more
wiley +1 more source
Demography and the statistics of lifetime economic transfers under individual stochasticity
Background: As individuals progress through the life cycle, they receive income and consume goods and services. The age schedules of labor income, consumption, and life cycle deficit reflect the economic roles played at different ages.
Hal Caswell, Fanny Annemarie Kluge
doaj +1 more source
ALDOA Promotes Glycolysis and NLRP3/GSDMD Pyroptosis to Accelerate ALS Progression
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is characterized by progressive motor neuron degeneration. Glycolytic dysregulation is implicated in disease progression, yet the underlying mechanisms remain unclear. This study investigates how Aldolase A (ALDOA) drives ALS progression through glycolysis‐mediated motor neuron pyroptosis.
Kaixin Yan +9 more
wiley +1 more source
Dynamic energy balanced max flow routing in energy-harvesting sensor networks
We propose a dynamic energy balanced max flow routing algorithm to maximize load flow within the network lifetime and balance energy consumption to prolong the network lifetime in an energy-harvesting wireless sensor network.
Bin Cai +3 more
doaj +1 more source
Time correlated single photon counter was design for measuring fluorescence lifetime of emitting materials. It was designed for photonics basic research and science that is usually done in a laboratory.
Isnaeni Isnaeni +2 more
doaj +1 more source
Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source
Nonparametric predictive inference with right-censored data [PDF]
This thesis considers nonparametric predictive inference for lifetime data that include right-censored observations. The assumption A((_m)) proposed by Hill in 1968 provides a partially specified predictive distribution for a future observation given ...
Yan, Ke-Jian
core
Dementia Incidence in Individuals With Parkinson's Disease in the Framingham Heart Study
ABSTRACT Limited information exists on incident dementia in individuals with Parkinson's disease (PD) in US community‐based samples. We examined cognitive statuses and PD diagnoses of 183 individuals in the Framingham Heart Study (FHS) to establish incident dementia, mortality rates, associations with sex, age at PD onset, and education level.
Joshi Dookhy +11 more
wiley +1 more source

