Results 111 to 120 of about 179,322 (291)

Biomechanics of the natural, arthritic, and replaced human ankle joint

Journal of Foot and Ankle Research, 2014
The human ankle joint complex plays a fundamental role in gait and other activities of daily living. At the same time, it is a very complicated anatomical system but the large literature of experimental and modelling studies has not fully described the ...
Alberto Leardini, John J O'Connor, Sandro Giannini   +2 more
doaj   +1 more source

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source

Early synovial regulatory T cell engagement in posttraumatic osteoarthritis

Arthritis &Rheumatology, Accepted Article.
Objective Posttraumatic osteoarthritis (PTOA) develops despite restoration of joint biomechanics, suggesting that early post‐injury biological processes within the synovium shape disease trajectories. We investigated whether synovial regulatory T (Treg) cells are engaged during the early phase following joint injury and whether experimental enrichment ...
Xueyou Zhang, Mingde Cao, Jianting Li, Bruma Sai‐Chuen Fu, Michael Tim‐Yun Ong, Patrick Shu‐Hang Yung   +5 more
wiley   +1 more source

Considering user experience and cognitive load in the design and development of a virtual reality application for embodied anatomy learning

Anatomical Sciences Education, EarlyView.
Abstract Virtual reality (VR) offers new possibilities for anatomy education through immersive and embodied interaction. Early‐stage evaluation of VR tools is necessary to assess user experience and perceived cognitive load and to guide iterative development.
Mélanie Gallot, Mira Hajj‐Hassan, Rawad Chaker, Christian Collet, Nady Hoyek   +4 more
wiley   +1 more source

Accurate Measurement in All‐inside Posterior Cruciate Ligament Reconstruction: A Technical Note

Arthroscopy Techniques, EarlyView.
Abstract With the increasing rate of posterior cruciate ligament reconstruction (PCLr) and growing adoption of the all‐inside PCLr, the existing literature lacks an optimal surgical protocol for this technique. It is well recognized that variations in knee size and intraoperative positioning pose challenges in determining the key parameter—the length ...
Daoliang Xu, Wei Yu, Zelin Jiang, Jianxia Wen, Xiaoyun Pan   +4 more
wiley   +1 more source

Fibrosis and Sports Injuries: Concept and Implications: The GESMUTE-SETRADE Consensus Statement

Orthopaedic Journal of Sports Medicine
Background: Musculoskeletal fibrosis can be frequently observed in the scope of sports medicine; however, there is no consensus regarding its definition, nor do we have substantial knowledge regarding its epidemiology or best therapeutic alternatives ...
J. D. Beas-Jiménez MD, A. León Garrigosa MD, P. Doñoro Cuevas MD, M. I. Álvarez Recio MD, C. Cofré Bolados MD, J. M. Alonso MD   +5 more
doaj   +1 more source

Lateral and Anterior Closing Wedge “9/9” Degree Osteotomy to Correct Both Tibia Vara and Excessive Tibial Slope

Arthroscopy Techniques, EarlyView.
Abstract High tibial osteotomy is a key option for patients with unicompartmental overload or instability. Although coronal correction for varus deformity is well established, excessive posterior tibial slope (PTS) is increasingly recognized as a contributor to anterior cruciate ligament graft failure.
Julien Druel, Antoine Piercecchi, Chris Wilson, Maher Ghandour, Kristian Kley, Matthieu Ollivier   +5 more
wiley   +1 more source

Cartilage tissue engineering using pre-aggregated human articular chondrocytes [PDF]

, 2008
In this study, we first aimed at determining whether human articular chondrocytes (HAC) proliferate in aggregates in the presence of strong chondrocyte mitogens.
Farhadi, J., J Farhadi, M Heberer, C Candrian, D Wendt, Wendt, D., A Barbero, Barbero, A., F Wolf, Wolf, F., Martin, I., Candrian, C., Heberer, M., I Martin   +13 more
core   +1 more source

Development of the human knee joint ligaments

, 1999
Methods: We summarize our observations on the development of the knee joint ligaments in 50 serially sectioned human embryonic and fetal lower limbs (26 embryos and 24 fetuses).
Mérida Velasco, Juan A., Sánchez Montesinos, Indalecio, Espín Ferra, Joaquín, Mérida Velasco, José Ramón, Rodríguez Vázquez, José Francisco, Jiménez Collado, Juan   +5 more
core   +1 more source

Arthroscopic Anterior Talofibular Ligament Repair Without Anchors for Chronic Lateral Ankle Instability

Arthroscopy Techniques, EarlyView.
Abstract In recent years, arthroscopic anterior talofibular ligament (ATFL) repair techniques have been increasingly used in the treatment of chronic ankle instability. Arthroscopic approaches not only allow for the management of concomitant intra‐articular pathologies but also help minimize wound‐related complications associated with open surgery and ...
Semih Yaş, Orkun Büyüksayın, Muhammet Özsoy, Mustafa Can Erdem, Mehmet Ali Tokgöz, Ulunay Kanatlı   +5 more
wiley   +1 more source