Results 121 to 130 of about 47,360 (313)

Tissue‐Specific and Spatially Dependent Metabolic Signatures Perturbed by Injury in Male and Female Mice

Arthritis &Rheumatology, EarlyView.
Objective Osteoarthritis, the leading cause of disability worldwide, disproportionately affects women, yet sex remains an overlooked determinant. This disparity stems from sex‐specific differences in injury susceptibility—a major risk factor for disease.
Hope D. Welhaven, Avery H. Welfley, Priyanka P. Brahmachary, Mark Greenwood, Donald F. Smith, Brian Bothner, Ronald K. June   +6 more
wiley   +1 more source

Sequential expression of Lgr5 and Col22a1 in developing synovial joints marks the progressive differentiation of progenitor cells to articular chondrocytes [PDF]

, 2014
Poster Presentation - Theme 3: Development & stem cellsHealthy articular cartilage in synovial joints provides a smooth, wear-resistant structure that reduces friction and absorbs impact forces.
Chan, D, Feng, C
core  

CD14 Plays a Critical Role in Pain and Inflammation Across Multiple Models of Post‐traumatic Osteoarthritis

Arthritis &Rheumatology, EarlyView.
Objective We employed global genetic deletion of CD14 and intra‐articular CD14 blockade across multiple murine osteoarthritis (OA) models that vary in severity of pathology and rate of progression to test the hypothesis that CD14 inhibition attenuates synovial inflammation and associated pain during disease progression.
Kevin G. Burt, Sanique M. South, Natalie S. Adamczyk, Vu Nguyen, Shingo Ishihara, Cheng Zhou, Kate L. Sharp, Sung Y. Kim, Anna E. Rapp, Baofeng Hu, Lance A. Murphy, Li‐Yin Hung, De'Broski Herbert, Joshua F. Baker, Robert L. Mauck, Timothy M. Griffin, Anne‐Marie Malfait, Rachel E. Miller, Carla R. Scanzello   +18 more
wiley   +1 more source

Novel application of gamification to support undergraduate anatomy: Student perceptions and performance

Anatomical Sciences Education, EarlyView.
Abstract Anatomy is a foundational component of various medical and paramedical disciplines. Existing research has suggested that games or game elements can improve student interest in musculoskeletal (MSK) anatomy. This project builds on previous gamification and serious game work and incorporates new anatomy‐based games into undergraduate anatomy ...
Emmeline Berger, Jacqueline Carnegie, Christopher J. Ramnanan   +2 more
wiley   +1 more source

Fibrosis and Sports Injuries: Concept and Implications: The GESMUTE-SETRADE Consensus Statement

Orthopaedic Journal of Sports Medicine
Background: Musculoskeletal fibrosis can be frequently observed in the scope of sports medicine; however, there is no consensus regarding its definition, nor do we have substantial knowledge regarding its epidemiology or best therapeutic alternatives ...
J. D. Beas-Jiménez MD, A. León Garrigosa MD, P. Doñoro Cuevas MD, M. I. Álvarez Recio MD, C. Cofré Bolados MD, J. M. Alonso MD   +5 more
doaj   +1 more source

Combined Reconstruction of the Medial Patellofemoral Ligament and the Medial Quadriceps Tendon–Femoral Ligament Using Rectus Femoris Tendon Autograft

Arthroscopy Techniques, EarlyView.
Abstract Patellofemoral instability remains a challenging condition, especially in skeletally immature patients, who are at increased risk of recurrence. The medial patellofemoral ligament has historically been the focus of surgical reconstruction; however, recent anatomic studies have also highlighted the medial quadriceps tendon–femoral ligament as ...
Lokman Kehribar, John P. Fulkerson, Ahmet Emin Okutan   +2 more
wiley   +1 more source

Multi-centre retrospective study of long-term outcomes following traumatic elbow luxation in 37 dogs [PDF]

, 2016
Calvo, I, Farrell, M, James, D, Jordan, C, Kulendra, E R, Kulendra, N J, Meeson, R L, Sajik, D M R   +7 more
core   +2 more sources

The TGFβ type I receptor TGFβRI functions as an inhibitor of BMP signaling in cartilage. [PDF]

, 2019
The type I TGFβ receptor TGFβRI (encoded by Tgfbr1) was ablated in cartilage. The resulting Tgfbr1 Col2 mice exhibited lethal chondrodysplasia. Similar defects were not seen in mice lacking the type II TGFβ receptor or SMADs 2 and 3, the intracellular ...
Baek, Jongseung, Chun, Hyelim, Lopez, Noah, Lyons, Karen M, Razavi, Peyman, Sadik, Joshua Elyahu, Shirazyan, Anna, Wang, Weiguang   +7 more
core  

Double‐Bundle Artificial Medial Patellofemoral Ligament Reconstruction Using a Femoral Suture‐Sliding Anchor and Patellar Staged Tension Adjustment

Arthroscopy Techniques, EarlyView.
Abstract Double‐bundle medial patellofemoral ligament reconstruction with artificial ligaments is a minimally invasive surgical option for recurrent patellar dislocation. However, it carries a risk of over‐tensioning, which may lead to restricted patellar mobility and anterior knee pain.
Ryo Sasaki, Takahiro Okawa, Taichi Nishimura, Teppei Hayashi, Kazuya Kaneda, Masaki Nagashima, Hideo Morioka   +6 more
wiley   +1 more source

Ankylosing Spondylitis: A summary and review [PDF]

, 1993
A review of the etiology, clinical, radiological and laboratory presentation, differential diagnosis and management.
Walker, B.F.
core   +1 more source