Results 211 to 220 of about 46,913 (292)

Proximal Tibial Resection for Bone Tumor and Prosthetic Reconstruction Combined with Medial Gastrocnemius Flap. [PDF]

JBJS Essent Surg Tech
Angelini A, Pala E, Trovarelli G, Cerchiaro M, Ruggieri P.   +4 more
europepmc   +1 more source

Mechanism of ITGB2 in Osteoclast Differentiation in Osteoarthritis

Cell Proliferation, EarlyView.
In osteoclast precursors, higher ITGB1 than ITGB2 expression increases ITGA2‐ITGB1 integrin. In OA, extracellular signals upregulate ITGB2 and downregulate ITGB1, enhancing ITGA2‐ITGB2 integrin. This activates Rac1 to Rac‐GTP, driving osteoclast differentiation. Hyperactive subchondral osteoclasts accelerate OA progression.
Yang Yang, Rui Sun, Zhibin Lan, Qi Ma, Gang Wu, Di Xue, Zhirong Chen, Yajing Su, Ye Ma, Xiaolei Chen, Jiangbo Yan, Long Ma, Xiaoxin He, Kuanmin Tian, Xiaoyi Ma, Xue Lin, Qunhua Jin   +16 more
wiley   +1 more source

A comparative analysis of different suture-button orientations for optimal dynamic stabilization of injured syndesmosis: A finite element study. [PDF]

Jt Dis Relat Surg
Taşar K, Gürsoy MK, Uğur L, Civan O, Özdemir H.   +4 more
europepmc   +1 more source

Inhibition of Fibroblast Activation Protein‐α Ameliorates Intervertebral Disc Degeneration via Reduced Vascular Invasion in Cartilage Endplate

Cell Proliferation, EarlyView.
Schematic illustration showing that FAP‐α promoted angiogenesis, cytokine release and ECM degradation in the CEP degeneration of the intervertebral disc through upregulating the PI3K/Akt/HIF‐1α/VEGFA pathway. ABSTRACT Intervertebral disc degeneration (IDD) is a primary cause of low back pain, with the development of new blood vessels being a key ...
Hao‐Wei Xu, Sheng‐Jie Chang, Shuo Wang, Xiao‐Wei Liu, Shan‐Jin Wang   +4 more
wiley   +1 more source

Biomechanical Analysis of 3D Printed and Thermoformed EVA Custom‐Made Mouthguard: Experimental and Finite Element Analyses

Dental Traumatology, EarlyView.
ABSTRACT Background/Objective 3D printed materials have been evaluated for fabricating mouthguards; however, little is known about their biomechanical performance in preventing dental trauma. This study aimed to compare two 3D printed polymers and three ethylene vinyl acetate (EVA) sheets used for mouthguard fabrication regarding their mechanical ...
Airin Karelys Avendaño Rondon, Izabela Batista Cordeiro, Maribí Isomar Terán Lozada, Gustavo Mendonça, Priscilla Barbosa Ferreira Soares, Paulo Sergio Borella, Carlos José Soares   +6 more
wiley   +1 more source

The role of radiography and MRI as screening tools and outcome measures in clinical trials of knee osteoarthritis: a perspective on the current status and outlook. [PDF]

Ther Adv Musculoskelet Dis
Roemer FW, Collins JE, Hochberg MC, Kompel AJ, Diaz LE, Hayashi D, Jarraya M, Hunter DJ, Guermazi A.   +8 more
europepmc   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Current and future advances in practice: cervical spondylosis and mechanical neck pain. [PDF]

Rheumatol Adv Pract
Jull G, Thomas L, Liang Z, Treleaven J.
europepmc   +1 more source

Repeated injection of pooled frozen allogeneic umbilical cord blood mesenchymal stromal cells in 5 flat‐racing horses

Equine Veterinary Education, EarlyView.
Summary Background Tendinopathies in racehorses are challenging to treat, and restoring normal tendon composition remains elusive despite extensive research. Equine multipotent mesenchymal stromal cells (MSC) have shown promise for tendon repair, and various sources of MSC have been described.
A. Merchan Muñoz, N. Coté, T. Koch, S. Mehrpouyan, A. H. Alizadeh, K. A. Russell, G. Monteith, J. Koenig   +7 more
wiley   +1 more source

Anatomical reconstruction of coracoclavicular and acromioclavicular ligaments using an autologous tendon graft provides excellent outcomes in acute acromioclavicular joint dislocation. [PDF]

Knee Surg Sports Traumatol Arthrosc
Konstantinou E, Koskiniotis A, Stefanou N, Koutalos A, Athanaselis E, Hantes M, Varitimidis S.   +6 more
europepmc   +1 more source