Results 121 to 130 of about 99,238 (312)

Targeting Dnmt3a/m5C/RelA Axis Attenuates Microglia Inflammatory Response and Improves Postoperative Recovery in Chronic Compressive Cervical Spinal Cord Injury

Advanced Science, EarlyView.
A pro‐inflammatory microglial subset persists after decompression in chronic compressive cervical spinal cord injury and shows enhanced Dnmt3a‐driven m5C signaling. By stabilizing RelA mRNA, this axis sustains NF‐κB activation and postoperative neuroinflammation.
Tianyu Qin, Yuan Jiang, Yongheng Xie, Huanwei Qu, Wenbin Yan, Jingle Chen, Yining Chen, Huayi Li, Naibo Feng, Jiajun Wu, Chao Zhang, Zhengqi Huang, Ming Shi, Zhihuai Deng, Guozhi Xiao, Houqing Long   +15 more
wiley   +1 more source

Human ligaments classification: a new proposal

, 2011
A high concern exists among physicians about surgically important ligaments such as cruciate and collateral ligaments of the knee, patellar ligament, tibiofibular syndesmosis, collateral ligaments of the ankle, and coracoclavicular ligament. However, the
Paraskevas, G.K.
core  

Biomechanical evaluation of the stabilizing function of the atlantoaxial ligaments under shear loading: A canine cadaveric study

, 2013
OBJECTIVES To evaluate the stabilizing function of atlanto-axial ligaments in dogs. STUDY DESIGN Cadaveric biomechanical study. ANIMALS Beagle dog cadavers (n = 10).
Ferguson, Stephen J, Bürki, Alexander, Gendron, Karine, Reber, Katrine, Stoffel, Michael Hubert, Forterre, Franck, Vizcaino Reves, Nuria   +6 more
core   +1 more source

Quantitative MRI Evaluation of Coracohumeral Ligament and Inferior Glenohumeral Capsule Thickening in Adhesive Capsulitis: Correlation with Range of Motion and Edema Patterns

Eurasian Journal of Medicine
Background: Adhesive capsulitis involves capsular fibrosis and restricted shoulder movements, particularly external rotation and abduction. Magnetic resonance imaging (MRI) enables assessment of capsular and ligamentous thickening.
Seda Soğukpınar Karaağaç, Nevzat Yeşilmen   +1 more
doaj   +1 more source

Biodegradable Zn‐Based Implants: Progress, Challenges, and Pathways toward Clinical Translation

Advanced Science, EarlyView.
Exploring biodegradable Zn‐based implants offers a promising pathway to next‐generation biomedical devices with balanced degradation and biocompatibility. A comprehensive overview of biodegradable Zn‐based implants, covering their biological significance, material design principles, and advanced engineering strategies is provided.
Panfeng Zhao, Zhengquan Wang, Hui Yang, Xiyuan Zhang, Hanyuan Liu, Xiaotong Lu, Xiaocheng Li, Yanyan Liu, Xi Zhao, Wenhao Zhou, Yufeng Zheng   +10 more
wiley   +1 more source

Congenital Absence of the Cruciate Ligaments

, 2000
Congenital absence of one or both cruciate ligaments is a rare event, and little literature exists regarding this abnormality.  Patients with this condition often have associated anomalies.
Amirault, J. David, Leahey, Lorne, Smith, Derek B.   +2 more
core   +1 more source

MORPHOLOGICAL ANALYSIS OF AGE DYNAMICS OF BIOMECHANICAL PROPERTIES OF KNEE LIGAMENTS OF THE KNEE JOINT IN HUMAN FETUSES

Сеченовский вестник, 2017
A study of the structure and biomechanical properties of knee joint ligaments in 200 fetus corpses at the age of 12 to 38 weeks of intrauterine development was conducted.
A. E. Strizhkov
doaj  

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

Beyond Potency: Emerging Determinants and Optimization Strategies Enhancing Therapeutic Efficacy of Adult Stem Cells

Advanced Science, EarlyView.
Adult stem cell therapy requires more than high in vitro potency. This review proposes a systems framework in which cell‐intrinsic programs, instructive microenvironmental cues, and pre‐/post‐delivery engineering are co‐designed under standardized translational rules.
Soo‐Rim Kim, Yun Jae Jung, Hwa‐Yong Lee   +2 more
wiley   +1 more source

Strain‐Adaptive Dielectric Metamaterials via Bioinspired “Ligament‐Bone” Architecture for Ultrahigh‐Energy Capacitive Storage

Advanced Science, EarlyView.
A bioinspired strain‐adaptive ligament‐bone architecture achieves record‐high energy density of 26.1 J cm−3 and 90% efficiency at 600 MV m−1, coupled with a Young's modulus of 2.13 GPa. ABSTRACT Polymer dielectrics for capacitive energy storage face fundamental trade‐offs between breakdown strength, energy density, efficiency, and mechanical robustness.
Jian Wang, Xinyu Wang, Jiabao Wang, Biyun Peng, Yifei Zhang, Ning Zhu, Xin Hu   +6 more
wiley   +1 more source