Zapnometinib treatment and influenza A virus infection modulate the HLA class I ligandome in human lung adenocarcinoma cells. [PDF]
Hamza H, Ghosh M, Rammensee HG, Planz O.
europepmc +1 more source
From Adult to Adolescent: Alignment in Clinical Trials and Outcomes in Axial Spondyloarthritis
Spondyloarthritis (SpA) is a group of chronic inflammatory diseases encompassing axial and peripheral forms, with up to 20% of patients developing symptoms before age 16. Despite this substantial pediatric burden, treatment options for juvenile‐onset SpA (JSpA), particularly those with axial disease (axJSpA), remain limited.
Pamela F. Weiss +9 more
wiley +1 more source
Imidazol-2-ylidene-Based NCCN Ligands for Chiral-at-Iron Catalysis. [PDF]
Hinterlang L, Ivlev SI, Meggers E.
europepmc +1 more source
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Iridium(III) Complexes Bearing Pyrene- and Anthracene-Functionalized Ligands-Photophysics and Application Potential in Photocatalysis, Triplet-Triplet Annihilation Upconversion, Photodynamic Therapy, and Photoactivated Chemotherapy. [PDF]
Kryczka A +3 more
europepmc +1 more source
This study applies machine learning regression to predict chromium layer thickness in decorative trivalent chromium electroplating, using 441 experiments from laboratory‐scale (1L) and pilot‐scale (14L) setups. Tree‐based models, particularly CatBoost, outperformed linear regression by capturing nonlinear parameter interactions (R2$R^2$ up to 0.77 ...
Christoph Baumer +4 more
wiley +1 more source
Mastering the potential of well-defined ML<sup>1</sup>L<sup>2</sup> species in asymmetric catalysis through ligand immobilization (ML<sup>het</sup>L<sup>hom</sup>). Use in highly enantioselective Pd-catalyzed spiroannulation. [PDF]
Biosca M +8 more
europepmc +1 more source
Solvate ionic liquids lubrication reduced the coefficient of friction by ∼60% compared to dry sliding, reaching steady‐state values as low as 0.04–0.05. Corrosion weight‐loss measurements in 1 M HCl further demonstrated significant inhibition behavior, with only 100 ppm of [Li(G3)][TFSI] (∼68.5 μL/L) reducing corrosion‐product weight loss by 63 ...
Sameh Dabees +6 more
wiley +1 more source
Direct arylation polymerization of electron-rich arenes with polar-group tolerance enabled by ligand-coordination tuning. [PDF]
Pei X +7 more
europepmc +1 more source

