Results 161 to 170 of about 86,842 (296)

RIPK3 Orchestrates Scar‐Associated Macrophage Dysfunction to Drive Pulmonary Fibrosis

Advanced Science, EarlyView.
Beyond signaling cell death, RIPK3 emerges as a critical metabolic regulator in pulmonary fibrosis. This research reveals that RIPK3 promotes PI3K‐AKT signaling in scar‐associated macrophages to fuel polyamine synthesis, independent of its kinase activity.
Tao Yang, Xiao Li, Shuyue Lei, Qingqing Li, Yi Zhang, Zhizhen Hui, Jinjin Ren, Xuelian Yang, Xiaoqian Yang, Chunlan Feng, Yousheng Xu, Dongxin Zhao, Wei Tang   +12 more
wiley   +1 more source

Ubiquitin E3 ligase KLHL6 brings exhausted T-cells back into action. [PDF]

Immun Inflamm
Chen Z, Bullock AN, Kessler BM.
europepmc   +1 more source

Alterations in the Biosynthesis of Lignin in Transgenic Plants with Chimeric Genes for 4-Coumarate: Coenzyme A Ligase [PDF]

, 1996
Shinya Kajita, Yoshihiro Katayama, Satoshi Omori   +2 more
openalex   +1 more source

Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis

Advanced Science, EarlyView.
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen, Haidong Yu, Dongjiang Lin, Guojun Yang, Yuchen Xie, Yang Zhang, Jifeng Yuan   +6 more
wiley   +1 more source

Enzymatic activities of proteins encoded by PmurB, PmurC, and PmurE involved in methanogen pseudomurein biosynthesis. [PDF]

Front Microbiol
Cha G, Lai Z, Wang S, Yang Q, Zhao P, Chen Y, Han W, Bai L.   +7 more
europepmc   +1 more source

Thermal unfolding curves of ligases #6, #7 and 10C.

, 2015
A Morelli, John Haugner, Burckhard Seelig   +2 more
openalex   +2 more sources

Evaluation of a commercial test based on ligase chain reaction for direct detection of Mycobacterium tuberculosis in respiratory specimens [PDF]

, 2004
Fabíola Karla Ribeiro, Valdério do Valle Dettoni, Renata Lyrio Peres, Solange Alves Vinhas, Tatiana Resende Có, Reynaldo Dietze, Moisés Palaci   +6 more
openalex   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

E2 variants for probing E3 ubiquitin ligase activities. [PDF]

Proc Natl Acad Sci U S A
Du J, Andree GA, Horn-Ghetko D, Stier L, Singh J, Kostrhon S, Kiss L, Mann M, Sidhu SS, Schulman BA.   +9 more
europepmc   +1 more source

The E3 ligase APC/C-Cdh1 regulates MEF2A-dependent transcription by targeting SUMO-specific protease 2 for ubiquitination and degradation

, 2015
Lu Han, Bin Liu, Fujun Zhang, Jin Zhang, Rong Dong, Lei Chen, Dongmei Qu, Yan Lu, Buwei Yu   +8 more
openalex   +1 more source