Results 161 to 170 of about 718,207 (427)

Assessing long-distance RNA sequence connectivity via RNA-templated DNA–DNA ligation

open access: yeseLife, 2015
Many RNAs, including pre-mRNAs and long non-coding RNAs, can be thousands of nucleotides long and undergo complex post-transcriptional processing. Multiple sites of alternative splicing within a single gene exponentially increase the number of possible ...
Christian K Roy   +4 more
doaj   +1 more source

Cardiac Organoid Model Inspired Micro‐Robot Smart Patch to Treat Myocardial Infarction

open access: yesAdvanced Materials, EarlyView.
The heart organoid model exhibits the acidic microenvironment characteristic of myocardial infarction, which emerges as a pivotal force propelling the movement of micro‐robots. These micro‐robots, administered through microneedles, can penetrate deep into the tissue, effectively delivering therapeutic payloads to facilitate heart repair.
Fangfang Wang   +12 more
wiley   +1 more source

Utilizing of protein splicing phenomenon for optimization of obtaining and purification of the recombinant human growth hormone [PDF]

open access: yesEurop J Medic Res., 2006, Oct. 8, vol.11 - p. 128-129, 2006
Protein splicing is a post-translational autocatalystic excision of internal protein sequence (intein) with the subsequent ligation of the flanking polypeptides (exteins). The high specificity of excision ensured by intein makes it possible to use a phenomenon of protein splicing for the biotechnology purposes.
arxiv  

Bias in Ligation-Based Small RNA Sequencing Library Construction Is Determined by Adaptor and RNA Structure

open access: yesPLoS ONE, 2015
High-throughput sequencing (HTS) has become a powerful tool for the detection of and sequence characterization of microRNAs (miRNA) and other small RNAs (sRNA).
Ryan T. Fuchs   +3 more
semanticscholar   +1 more source

Orbital Varix and Its Surgical Correction - A Case Report

open access: yesIndian Journal of Plastic Surgery, 1993
A Young patient presented with left unilateral proptosis and Orbital venography was suggestive of orbital vari on left side. An easy and effective operative procedure was planned. The superficial veins around orbit were ligated. Result was acceptable and
Dr. P.K. Sharma   +3 more
doaj   +1 more source

DNA‑Directed Assembly of Photonic Nanomaterials for Diagnostic and Therapeutic Applications

open access: yesAdvanced Materials, EarlyView.
DNA‐directed assembly offers a powerful strategy for constructing structured photonic nanomaterials with precise spatial control. This review provides a comprehensive overview of recent advancements in DNA‐assembled photonic nanomaterials for diagnostics and therapeutics, highlighting key design principles, functionalization strategies, and optical ...
Longjiang Ding   +5 more
wiley   +1 more source

Simulation of Heme using DFT+U: a step toward accurate spin-state energetics [PDF]

open access: yesarXiv, 2007
We investigate the DFT+U approach as a viable solution to describe the low-lying states of ligated and unligated iron heme complexes. Besides their central role in organometallic chemistry, these compounds represent a paradigmatic case where LDA, GGA, and common hybrid functionals fail to reproduce the experimental magnetic splittings.
arxiv  

Left Atrial Appendage Ligation in Patients With Atrial Fibrillation Leads to a Decrease in Atrial Dispersion

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2015
Background Left atrial appendage (LAA) exclusion has been performed in patients with atrial fibrillation (AF) to prevent thrombus formation and subsequent cardioembolic events. Left atrial electrical remodeling is a recognized factor in the recurrence of
Mitsuharu Kawamura   +3 more
doaj   +1 more source

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