Results 201 to 210 of about 81,649 (382)
ANEURYSM OF THE INNOMINATE ARTERY TREATED BY PROXIMAL LIGATURE [PDF]
H. S. Souttar
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Neural tube defects (NTDs) are among the most common congenital malformations. However, the underlying etiology and mechanism remain elusive. Here, the role of DNA double‐strand breaks (DSBs) in 3D genome organization within the NTDs with folate deficiency is reported.
Ting Zhang +12 more
wiley +1 more source
A Caseof Aneurism by Anastomosis in the Orbit, Cured by the Ligature of the Common Carotid Artery [PDF]
Benjamin Travers
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Integrin α8‐Mediated Pericyte Morphogenesis Controls Blood‐Brain Barrier Integrity
This study highlights that ITGA8 impacts pericyte morphology and function, both crucial for BBB integrity, via RhoA/ROCK signaling, thus influencing TGF‐β1 activation through cytoskeletal tension and ECM interactions. Notably, in post‐ischemic recovery models, ITGA8 deficiency exacerbates vascular dysfunction by impairing pericyte‐mediated BBB ...
Chang‐Xiong Gong +16 more
wiley +1 more source
FBXO44 promotes colorectal cancer progression by targeting FOXP1 for ubiquitin‐mediated degradation. This study reveals a phosphorylation‐dependent mechanism involving AURKA and highlights the FBXO44/FOXP1/Cyclin E2 axis as a potential therapeutic target in colorectal cancer.
Hongxu Nie +10 more
wiley +1 more source
ON A RECENT CASE OF LIGATURE OF THE EXTERNAL ILIAC ARTERY BY AN ANTISEPTIC MATERIAL, FOR THE CURE OF AN UNUSUAL NUMBER OF ANEURISMS. [PDF]
Oliver Pemberton
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D‐glucuronyl C5‐Epimerase Binds to EGFR to Suppress Kidney Fibrosis
Glucuronyl C5‐epimerase (Hsepi, gene name Glce) is a key enzyme catalyzing heparan sulfate (HS) chain biosynthesis in HS proteoglycans, which are ubiquitously expressed on cell membranes. In normal renal tubular cells, Glce binds to the intracellular domains of EGFR, maintaining stable and orderly EGFR phosphorylation.
Xiaoqi Jing +9 more
wiley +1 more source

