Results 141 to 150 of about 38,654 (229)

Harmonizing Rigidity and Flexibility: Embedding COF Quantum Dots Into Extracellular Matrix Gel as Carbon Monoxide Depot for Acoustically Triggered Time‐Programmable Anti‐Infective Therapy

Advanced Science, EarlyView.
A rigid‑flexible integrated CO depot is engineered by embedding rigid COFQDs into a flexible ECM gel network. The rigid framework enables high‑capacity CO storage and sonodynamic bacterial killing, while the flexible ECM gel controls sustained CO release, collectively eradicating multidrug‑resistant infection and promoting scarless healing.
Baohong Sun, Fang Han, Chunxiao Zhu, Zhiyuan Yang, Haoru Wang, Jinpei Mei, Jie Chen, Jingwen Zhu, Zihan Bo, Taju Wu, Xiaogang Zhou, Tao Ma, Yutian Su, Youhui Lin   +13 more
wiley   +1 more source

Light-sheet fluorescence microscopy for the in vivo study of microtubule dynamics in the zebrafish embryo. [PDF]

Biomed Opt Express, 2021
Bernardello M, Marsal M, Gualda EJ, Loza-Alvarez P.   +3 more
europepmc   +1 more source

A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers

Advanced Science, EarlyView.
Phase separation and aging of intrinsically disordered proteins are placed in a unifying framework. A thermodynamically consistent time‐dependent version of associating‐polymer theory shows how the processes are intricately coupled. Assuming aging to occur through interacting sites resulting from reversible conformational transitions, the model ...
Jasper J. Michels, Joana Caria, Edward A. Lemke   +2 more
wiley   +1 more source

Multimodal optical coherence tomography and two-photon light sheet fluorescence microscopy for embryo imaging. [PDF]

J Biomed Opt
Karim MM, Sun R, Khajavi B, Singh M, Ambekar YS, Schill AW, Aglyamov SR, Mayerich D, Larin KV.   +8 more
europepmc   +1 more source

Digital Brain Maps and Virtual Neuroscience: An Emerging Role for Light-Sheet Fluorescence Microscopy in Drug Development. [PDF]

Front Neurosci, 2022
Perens J, Hecksher-Sørensen J.
europepmc   +1 more source

Deep‐Learning‐Driven High‐Fidelity In Vivo Hyperspectral Fluorescence Imaging Under Extreme Photon‐Limited Conditions

Advanced Science, EarlyView.
Highly overlapping fluorescent signals become distinguishable in photon‐limited living organisms via advanced imaging with intelligent reconstruction. The resulting in vivo hyperspectral imaging capability reveals nanoplastic uptake and circulation in live zebrafish, providing a new approach for studying complex biological and environmental processes ...
Renjian Li, Shutao Wu, Kaixiang Li, Zhenyu An, Yuwen Ben, Guiye LI, Sunil Kumar, James Mcginty, Tawfique Hasan, Songnian Fu, Meng Zhang, LingLing Chen   +11 more
wiley   +1 more source

Illuminating Satellite Cells: Light Sheet Fluorescence Microscopy for 3D Imaging of Murine Skeletal Muscles Damaged by Ex Vivo Forced Eccentric Contraction. [PDF]

Microsc Res Tech
Garella R, Imbimbo E, Palmieri F, Tani A, Parigi M, Chellini F, La Contana A, Belmonte MM, Longhin A, Silvestri L, Sassoli C, Squecco R.   +11 more
europepmc   +1 more source

Light sheet fluorescence microscopy for the investigation of blood-sucking arthropods dyed via artificial membrane feeding. [PDF]

Parasit Vectors, 2022
Ten Bosch L, Habedank B, Candeo A, Bassi A, Valentini G, Gerhard C.   +5 more
europepmc   +1 more source

B Cells are Activated via a Nanoporous Interface that Stabilizes Microvilli and Engages Mechanosensitive Ion Channels

Advanced Science, EarlyView.
B cells can be activated independently of antigen recognition via mechanical stimulation through nanoporous substrates. Exposure to such substrates induced B cell microvilli extension into the pores, intracellular Ca2+ signaling, phosphorylation of signaling proteins, and CD69 expression.
Nozie D. Aghaizu, Willi Weber, Nadine Strempel, Asya Polat, Enrico Klotzsch   +4 more
wiley   +1 more source

First application of three-dimensional light sheet fluorescence microscopy to human testicular tumors: New perspectives in histopathology. [PDF]

Andrology
Pinkert-Leetsch D, Kareem A, Merz SF, Teckentrup M, Fichtner A, Bremmer F, Missbach-Guentner J.   +6 more
europepmc   +1 more source