Results 121 to 130 of about 4,545,693 (268)

TREX1, a predator for treating MSI‐H tumors?

Molecular Oncology, EarlyView.
Immunotherapy benefits many patients; yet, some with MSI‐H tumors remain unresponsive despite their high immunogenicity. Xu et al. reveal that TREX1 enables immune evasion by degrading cytosolic DNA and suppressing cGAS–STING–IFN‐I signaling. TREX1 loss restores DNA sensing, increases CD8+ T and NK cell infiltration, and boosts antitumor immunity ...
Elena Benidovskaya, Joséphine Deneft, Marc Van den Eynde   +2 more
wiley   +1 more source

Photodynamic inactivation of Mycobacterium tuberculosis by broad-spectrum visible light. [PDF]

Appl Microbiol Biotechnol
D'Agostini C, Prezioso C, Checconi P, Camicia V, Pelliccioni M, Di Traglia L, Minieri M, Legramante JM, Garaci E, Limongi D.   +9 more
europepmc   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

Treatment Guidelines for Nosocomial Pneumonia: Agreeing to Disagree

Canadian Journal of Infectious Diseases, 1993
R Bruce Light
doaj   +1 more source

LED lighting (350-650nm) undermines human visual performance unless supplemented by wider spectra (400-1500nm+) like daylight. [PDF]

Sci Rep
Barrett EM, Jeffery G.
europepmc   +1 more source

Light propagation in dry and wet softwood

, 2008
Alwin Kienle, Cosimo D’Andrea, Florian Foschum, Paola Taroni, Antonio Pifferi   +4 more
openalex   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

Gavin Slade, Reorganizing crime: Mafia and anti-Mafia in post-Soviet Georgia

Journal of Power Institutions in Post-Soviet Societies, 2016
Matthew Light
doaj  

Dragonfly red opsins share a common tuning mechanism with mammalian red opsins and further enhancement of near-infrared sensitivity. [PDF]

Cell Mol Life Sci
Sato R, Terakita A, Koyanagi M.
europepmc   +1 more source

Visible-Light Photocatalytic Degradation of Aniline Blue by Stainless-Steel Foam Coated with TiO2 Grafted with Anthocyanins from a Maqui-Blackberry System [PDF]

, 2020
Dreidy Vásquez, Francisca Palominos, S. Giraldez Martinez   +2 more
openalex   +1 more source