Results 101 to 110 of about 13,459,474 (298)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Rejection versus forceful imposition during elections: the ‘I have come to stay’ mindset of the incumbent

open access: yesHumanities & Social Sciences Communications
Political actors may resort to drastic measures, including election-related violence, to pursue electoral victory. While free and fair elections are fundamental to any democratic system, electoral violence threatens the integrity of this process and ...
Light Iwhuechiokike Nyeche
doaj   +1 more source

Advanced Unmanned Aerial Vehicles for Improved Communications [PDF]

open access: yes
Reestablishing communication channels is one of the most important yet time-consuming procedures to carry out following a natural disaster. After Hurricane Katrina impacted Louisiana in 2005, more than 60% of networks were still down 3 weeks after the ...
Light, Bailey G.
core   +1 more source

Getting from research to practice in M4D [PDF]

open access: yes, 2010
In this paper we argue that, if technical M4D research is going to contribute positively to development, the activities of specialized, highly paid ‘researchers’ must be combined with skilled contributions from many other actors. In particular, there is
Dearden, Andy   +3 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Why Parents Play Favorites: Explanations for Unequal Bequests [PDF]

open access: yes
Economists have invested a great deal of effort in trying to understand the motivation for family transfers, yet recent empirical work testing the seemingly appealing models of altruism and exchange has led to decidedly mixed results.
Audrey Light, Kathleen McGarry
core   +3 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Light-Light Scattering

open access: yes, 2011
For a long time, it is believed that the light by light scattering is described properly by the Lagrangian density obtained by Heisenberg and Euler. Here, we present a new calculation which is based on the modern field theory technique. It is found that the light-light scattering is completely different from the old expression.
openaire   +2 more sources

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

open access: yesMolecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy