Results 81 to 90 of about 13,459,474 (298)
The Evolution of EU policy towards its CIS neighbours [PDF]
When the EU began to plan enlargement, it was important to define and establish a new relationship with the successor states to the Soviet Union. This paper traces the evolution of the EU's policy towards those successor states from 1991 until the ...
Margot Light
core
, 2007 The error between appropriately smooth functions and their radial basis function interpolants, as the interpolation points fill out a bounded domain in R^d, is a well studied artifact. In all of these cases, the analysis takes place in a natural function
F.J. Narcowich +8 more
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
FEBS Letters, EarlyView.AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Responses of Study Abroad Students in Australia to Experience-Based Pedagogy in Sport Studies
International Journal for the Scholarship of Teaching and Learning, 2008 This paper contributes to research on the scholarship of teaching in the physical education/sport studies fields by examining the responses of study abroad students from overseas studying in Australia to a unit of study in sport studies that placed the ...
Richard Light, Steve Georgakis
doaj +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Network analysis of metabolic enzyme evolution in
BMC Bioinformatics, 2004 Background The two most common models for the evolution of metabolism are the patchwork evolution model, where enzymes are thought to diverge from broad to narrow substrate specificity, and the retrograde evolution model, according to which enzymes ...
Kraulis Per, Light Sara
doaj +1 more source
Beyond enterprise resource planning projects: innovative strategies for competitive advantage [PDF]
, 1999 A rapidly changing business environment and legacy IT problems has resulted in many organisations implementing standard package solutions. This 'common systems' approach establishes a common IT and business process infrastructure within organisations and
Holland, C, Kawalek, P, Light, BA
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Reconfiguring Socialist Urban Landscapes: The ‘Left-Over’ Spaces of State-Socialism in Bucharest [PDF]
Human Geographies: Journal of Studies and Research in Human Geography, 2010 The end of state-socialism has produced complex processes of urban change in East and Central Europe including the reshaping of urban identities and urban cultural landscapes in post-socialist cities.
Duncan Light , Craig Young
doaj
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source