Results 91 to 100 of about 13,459,474 (298)
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Finding a Future for Environmental Ethics [PDF]
Les Ateliers de l’Ethique, 2012 Andrew Light
doaj +1 more source
Evidence for a heritable predisposition to Chronic Fatigue Syndrome
BMC Neurology, 2011 Background Chronic Fatigue Syndrome (CFS) came to attention in the 1980s, but initial investigations did not find organic causes. Now decades later, the etiology of CFS has yet to be understood, and the role of genetic predisposition in CFS remains ...
Bateman Lucinda +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
User resistance strategies and the problems of blanket prescriptions: a case study of resistance success [PDF]
, 2006 There is a growing body of research on resistance in IS projects, a good deal of which focuses on strategies for overcoming resistance. However, within this strand of research, it appears that there is a ‘blanket prescription’ approach that does not ...
Griffiths, M, Light, BA
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Heath Network Clinicians Use and Need for Clinical Information Sources: Results of a Survey [PDF]
, 2018 The Dana Medical Library, part of the University of Libraries system, with the support of the University of Vermont Health Network, assessed the needs of UVM Health Network clinicians for evidence-based clinical resources such as: medical databases ...
Burke, Marianne, Light, Jeanene
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Using HEC-FIA to identify Indirect Economic Losses
E3S Web of Conferences, 2016 The United States Army Corps of Engineers’ Hydrologic Engineering Center developed the HEC-FIA (Flood Impact Analysis) software to assist in the estimation of consequences with uncertainty.
Lehman William, Light Miles
doaj +1 more source
Brokering between heads and hearts: an analysis of designing for social change [PDF]
, 2009 This paper describes a fluid and responsive design process identified among certain practitioners involved in solving social problems or inspiring social change.
Light, Ann, Miskelly, C.
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