Results 41 to 50 of about 13,459,474 (298)

Imaginative Geographies, Dracula and the Transylvania ‘Place Myth’ [PDF]

open access: yesHuman Geographies: Journal of Studies and Research in Human Geography, 2008
Imaginative geographies have become a central concept in Anglo-American cultural geography in recent years. We all form knowledge, ideas and beliefs in our minds about what other places are ‘like’.
Duncan Light
doaj  

Using EEG-Guided Basket and Umbrella Trials in Psychiatry: A Precision Medicine Approach for Cognitive Impairment in Schizophrenia

open access: yesFrontiers in Psychiatry, 2018
Due to advances over the last several decades, many fields of medicine are moving toward a precision medicine approach where treatments are tailored to nuanced patient factors. While in some disciplines these innovations are commonplace leading to unique
Yash B. Joshi   +2 more
doaj   +1 more source

Regulatory Horcruxes [PDF]

open access: yes, 2018
The regulator that designs and first implements a federal regulatory program does not always have the ability to control the timing and process of how that regulatory program will, in this Symposium’s language, “exit.” As the 2016 election has ...
Light, Sarah E.
core   +1 more source

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

open access: yesFEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Identification of a Non-Pentapeptide Region Associated with Rapid Mycobacterial Evolution. [PDF]

open access: yesPLoS ONE, 2016
A large portion of the coding capacity of Mycobacterium tuberculosis is devoted to the production of proteins containing several copies of the pentapeptide-2 repeat, namely the PE/PPE_MPTR proteins.
Per Warholm, Sara Light
doaj   +1 more source

Risky business: when a CRM vendor masqueraded as an ERP specialist [PDF]

open access: yes, 2007
Taking a social shaping perspective we unpack the development trajectory of a packaged software product to show, that contrary to mainstream accounts, design is not completely specified a-priori and that the process continues throughout implementation,
Griffiths, M, Light, BA
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

“Light from Light”

open access: yesThe Ecumenical Review, 2023
AbstractThis article examines the phrase “light from light” in the 4th‐century Nicene and Nicene‐Constantinopolitan creeds. The article begins by presenting the earliest use of light as a metaphor for Christ and his agency, as well as examples of similar language outside “orthodox” Christianity.
openaire   +2 more sources

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