Results 51 to 60 of about 3,893,782 (263)

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

On Pauli matrices and the implied spacetime geometry

open access: yesFrontiers in Physics
The commutator identity, 12σz,σx≡iσy, is shown to be equivalent to P≡momentum,X≡position=iℏI over the eigenspace of σy spanned by 1i, where 1≡1,0,0≡eX∈R3, i≡0,1∈C1≡Ry,z2, and 1,i≡eX⊕ez so that the particle travels along eX with its associated wave ...
Gregory L. Light
doaj   +1 more source

Verso il cielo: la Comunicazione Mediata da Computer a supporto dei corsi universitari tradizionali

open access: yesItalian Journal of Educational Technology, 1997
Riflessioni sull’uso della posta elettronica come strumento di discussione e di apprendimento per studenti universitari in campus.
Christofer Colbourn, Paul Light
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Responses of Study Abroad Students in Australia to Experience-Based Pedagogy in Sport Studies

open access: yesInternational Journal for the Scholarship of Teaching and Learning, 2008
This paper contributes to research on the scholarship of teaching in the physical education/sport studies fields by examining the responses of study abroad students from overseas studying in Australia to a unit of study in sport studies that placed the ...
Richard Light, Steve Georgakis
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Sharing Economy vs Sharing Cultures? Designing for social, economic and environmental good [PDF]

open access: yesInteraction Design and Architecture(s), 2015
This paper explores the story behind a crowdfunding service as an example of sharing technology. Research in a small neighborhood of London showed how locally-developed initiatives can differ in tone, scale, ambition and practice to those getting ...
Ann Light, Clodagh Miskelly
doaj  

Network analysis of metabolic enzyme evolution in Escherichia coli

open access: yesBMC Bioinformatics, 2004
Background The two most common models for the evolution of metabolism are the patchwork evolution model, where enzymes are thought to diverge from broad to narrow substrate specificity, and the retrograde evolution model, according to which enzymes ...
Kraulis Per, Light Sara
doaj   +1 more source

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