Results 51 to 60 of about 17,219,574 (393)
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro+2 more
wiley +1 more source
Engaging Students and Faculty in the Evaluation of a USMLE Review Product: Implications for Library Collection Development [PDF]
Introduction: Study materials for USMLE exams are some of the most commonly requested materials at Dana Medical Library. In Fall 2015, the Dana Medical Library received several student requests for online USMLE preparation materials.
Light, Jeanene, Stokes, Alice
core +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt+8 more
wiley +1 more source
Light Sources and Lighting Circuits
According to machinery statistics of the Ministry of Economy, Trade and Industry, the quantity of electric lamps produced in Japan was 613,000,000 (68.1% compared to the previous year). Of these, 73,000,000 were general lamps (88.1% compared to the previous year) and 32,000,000 were halogen lamps (79.3% compared to the previous year).
Takeo Yasuda+7 more
openaire +6 more sources
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
Brokering between heads and hearts: an analysis of designing for social change [PDF]
This paper describes a fluid and responsive design process identified among certain practitioners involved in solving social problems or inspiring social change.
Light, Ann, Miskelly, C.
core
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao+7 more
wiley +1 more source
Implementing effective antimicrobial therapy close to the onset of infection lowers morbidity and mortality and attenuates the spread of antimicrobial resistance.
Larry Burg+13 more
doaj +1 more source
Risky business: when a CRM vendor masqueraded as an ERP specialist [PDF]
Taking a social shaping perspective we unpack the development trajectory of a packaged software product to show, that contrary to mainstream accounts, design is not completely specified a-priori and that the process continues throughout implementation,
Griffiths, M, Light, BA
core +1 more source
Libri-Light: A Benchmark for ASR with Limited or No Supervision [PDF]
We introduce a new collection of spoken English audio suitable for training speech recognition systems under limited or no supervision. It is derived from open-source audio books from the LibriVox project.
Jacob Kahn+14 more
semanticscholar +1 more source