Results 51 to 60 of about 15,887,789 (404)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Frontiers in Psychiatry, 2018 Due to advances over the last several decades, many fields of medicine are moving toward a precision medicine approach where treatments are tailored to nuanced patient factors. While in some disciplines these innovations are commonplace leading to unique
Yash B. Joshi +2 more
doaj +1 more source
Sculpting light with paper for computational mobile phone microscopy [PDF]
arXiv, 2020 Many optical microscopy techniques rely on structured illumination by way of a projected image (eg. structured illumination microscopy) or a tailored angular distribution of light (eg. ptychography). Electro-optical equipment such as spatial light modulators and light emitting diode (LED) arrays are commonly used to sculpt light for these imaging ...
arxiv
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Identification of a Non-Pentapeptide Region Associated with Rapid Mycobacterial Evolution. [PDF]
PLoS ONE, 2016 A large portion of the coding capacity of Mycobacterium tuberculosis is devoted to the production of proteins containing several copies of the pentapeptide-2 repeat, namely the PE/PPE_MPTR proteins.
Per Warholm, Sara Light
doaj +1 more source
THz light amplification by an visible light laser in the presence of the plasma density gradient [PDF]
arXiv, 2020 A new mechanism for the THz light amplification is identified ina non-resonant Raman scattering between the THz light and a visible light lasers. The non-resonant scattering normally does not exchange the energy between E \&M fields, but the presence of the plasma density gradientcreates an condition in which a visible light laser could transfer its ...
arxiv
Designing the Born-Digital Archive [PDF]
, 2010 Light spoke generally about the major issues facing archivists who manage born digital records and how the UCI Libraries responded when providing access to the Richard Rorty papers.
Light, Michelle
core +1 more source
FEBS Letters, EarlyView.Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard +7 more
wiley +1 more source
The Electric Light for Light-Houses and Search-Lights [PDF]
Science, 1885 n ...
openaire +2 more sources