Results 61 to 70 of about 859,267 (264)
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
FEBS Letters, EarlyView.Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley +1 more source
Applied SciencesAn analytical approach is developed for calculating a phase diffraction axicon with angularly variable spatial frequency that generates a prescribed light curve without iteratively solving an inverse design problem: the axicon frequency function is ...
Svetlana N. Khonina +5 more
doaj +1 more source
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Classification of Exoplanetary Light Curves Using Artificial Intelligence
AIIn this article, we propose a robust star classification methodology leveraging light curves collected from 15 datasets within the Kepler field in the visible optical spectrum.
Leticia Flores-Pulido +3 more
doaj +1 more source
SYNTHETIC LIGHT CURVE OF R CORONAE BOREALIS
Odessa Astronomical Publications, 2017 The model for brightness variations of CrB is proposed.
A. F. Pugach, G. U. Kovalchuk
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Three Stages in Evolution of the Object Th4-4
GalaxiesThe results of observations of the object Th4-4 in 1970–2024 showed that during this period the object went through several stages, when its characteristics corresponded to different classes of objects: Be star, symbiotic star and planetary nebula ...
Lyudmila Kondratyeva +5 more
doaj +1 more source
Photometric Light Curve Analysis of ET Leo
Zanco Journal of Pure and Applied Sciences, 2019 In this work, the short period system named (ET Leo) have been chosen to be analyzed with B , V and R light curves with the Wilson-Devinney code and the results of orbital parameters of the system were obtained and compared with those obtained from ...
Aven M. Hamedamen, Ismail M. Murad
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source