Results 71 to 80 of about 859,267 (264)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Material Property Sensitivity of Light Curve Attitude Estimation for the Lunar Trailblazer
Earth and Space ScienceThe Lunar Trailblazer (LTB) spacecraft launched on 27 February 2025, toward a planned low‐lunar orbit. Eleven hours into its mission, contact with Trailblazer was lost, and recovery efforts began.
Liam Robinson +3 more
doaj +1 more source
Classification of Variable Star Light Curves with Convolutional Neural Network
GalaxiesThe classification of variable stars is essential for understanding stellar evolution and dynamics. With the growing volume of light curve data from extensive surveys, there is a need for automated and accurate classification methods. Traditional methods
Almat Akhmetali +6 more
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Light Curve Analysis of SAO23229 [PDF]
Journal of Astronomy and Space Sciences, 1993 We have made UBV light curves of a newly discovered eclipsing binary, SAO23229 at Sobaeksan Astronomy Observatory. We determined a minimum light time of HJD2448636.1170+/-0.0005 that is 3 minutes later than predicted time, and founda peculiar light ...
Ho-Il Kim +3 more
doaj
Multiwavelength light curve parameters of Cepheid variables
EPJ Web of Conferences, 2017 We present a comparative analysis of theoretical and observed light curves of Cepheid variables using Fourier decomposition. The theoretical light curves at multiple wavelengths are generated using stellar pulsation models for chemical compositions ...
Bhardwaj Anupam +5 more
doaj +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
Light Curve Variations of AR Lacertae [PDF]
Journal of Astronomy and Space Sciences, 1991 Sixteen unitary Light curves of AR Lac in B and V are made at Yonsei University Observatory in the period of 1980-1988. Some overview findings of light variations are made.
Il-Seong Nha
doaj
LIGHT CURVE TYPES OF CLASSIC T TAURI STARS
Odessa Astronomical Publications, 2016 By using the archive photometric data’s obtained for a long time intervals we have carried out a master light curves of 28 classical T Tauri type stars. For the physical character of variability mainly 5 type light curves can be separated.
N. Z. Ismailov, H. N. Adygezalzade
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source