Results 71 to 80 of about 2,259,814 (348)
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Light curve analysis of the late type binary V523 Cassiopeiae [PDF]
Serbian Astronomical Journal, 2009 We present the analysis of V and R light curves of the late type contact binary V523 Cas for the season of 2006. These observations make part of the monitoring program aimed at studying the long-term light curve variability in this system.
Latković O., Zboril M., Đurašević G.
doaj +3 more sources
The anabolic steroid stanozolol is a potent inhibitor of human MutT homolog 1
FEBS Letters, EarlyView.MutT homolog 1 (MTH1) is a member of the NUDIX superfamily of enzymes and is an anticancer drug target. We show that stanozolol (Stz), an anabolic steroid, is an unexpected nanomolar inhibitor of MTH1. The X‐ray crystal structure of the human MTH1–Stz complex reveals a unique binding scaffold that could be utilized for future inhibitor development ...
Emma Scaletti Hutchinson +7 more
wiley +1 more source
Modeling the TESS Light Curve of Ap Si Star MX TrA
UniverseThe TESS light curve of the silicon Ap star MX TrA was modeled using the observational surface distribution of silicon, iron, helium, and chromium obtained previously with the Doppler Imaging technique.
Yury Pakhomov +3 more
doaj +1 more source
Light Curve Analysis of Contact Binary System V523 Cassiopeiae [PDF]
Journal of Astronomy and Space Sciences, 2002 A total of 616 observations (308 in B, 308 in V) for V523 Cas was made on three nights from October 19 to 21 in 1999 using the 1.8m telescope with 2K CCD camera of the Bohyunsan Optical Astronomy Observatory of KAO.
J. H. Kim, J. H. Jeong
doaj +1 more source
The Near Infrared and Multiwavelength Afterglow of GRB 000301c [PDF]
, 2000 We present near-infrared observations of the counterpart of GRB 000301c. The K' filter (2.1 micron) light curve shows a well-sampled break in the decay slope at t=3.5 days post-burst.
Andrew S. Fruchter +3 more
core +2 more sources
FEBS Letters, EarlyView.Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield +3 more
wiley +1 more source
SYNTHETIC LIGHT CURVE OF R CORONAE BOREALIS
Odessa Astronomical Publications, 2017 The model for brightness variations of CrB is proposed.
A. F. Pugach, G. U. Kovalchuk
doaj +1 more source
Observations and light curve solutions of four ultrashort-period binaries [PDF]
Serbian Astronomical Journal, 2016 The paper presents light curve solutions of our observations of four new ultrashort-period eclipsing binaries with MS components. Two of them have periods almost at the upper limit (0.22 days) of the ultrashort-period binaries, while the periods
Kjurkchieva D. +3 more
doaj +1 more source