Results 141 to 150 of about 665,153 (306)

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

The shift of light intensity-ERG response curves after light manipulations.

, 2016
(A) Mean ERG b-waves of the 24 hours dark exposed (DE) rats (n = 8, red) and normally reared rats (n = 6, blue), SEM is shown as the shadow. (B) Light intensity-ERG amplitude curves to the 8 light intensities for the 24 hours dark exposed (prolonged DE) (
Hongbo Yu (398000), Dake Li (2940168), Qi Fang (199280)   +2 more
core   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Typical X-Ray Outburst Light Curves of Aql X-1

The Astrophysical Journal
We show that the typical X-ray outburst light curve of Aql X-1 can be reproduced by accretion onto a neutron star in the frame of the disk instability model without invoking partial accretion or the propeller effect.
Ömer Faruk Çoban, Ünal Ertan
doaj   +1 more source

Reconstruction of Cepheid radial velocity curves from the shape of the V-band light curves

Astronomy & Astrophysics
Context. Radial velocity (RV) curves of Cepheids are essential for studying their pulsation properties and also for measuring their distance via the parallax-of-pulsation method.
Hocdé V., Moskalik P., Nardetto N., Kervella P., Pilecki B., Smolec R., Pietrzyński G., Gieren W., Hajdu G., Gallenne A., Bailleul M. C., Bras G., Wielgórski P., Breuval L., Mérand A., Rathour R. S., Espinoza-Arancibia F., Kiviaho W., Apostolova B., Sivkova K.   +19 more
doaj   +1 more source

Extraction of spin periods of space debris from optical light curves

, 2015
The population of space debris increased drastically during the last years. These objects have become a great threat for active satellites. Because the relative velocities between space debris and satellites are high, space debris objects may destroy ...
Hager, Monika, Linder, Esther, Schildknecht, Thomas, Silha, Jiri   +3 more
core  

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Classification of Exoplanetary Light Curves Using Artificial Intelligence

AI
In this article, we propose a robust star classification methodology leveraging light curves collected from 15 datasets within the Kepler field in the visible optical spectrum.
Leticia Flores-Pulido, Liliana Ibeth Barbosa-Santillán, Ma. Teresa Orozco-Aguilera, Bertha Patricia Guzman-Velázquez   +3 more
doaj   +1 more source