Results 181 to 190 of about 1,240,084 (305)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Hydrocracking of Waste Plastic Pyrolysis Oil and Light Cycle Oil (PPO/LCO) Blends in a Trickle-Bed Reactor: Catalyst Assessment and Operating-Condition Screening. [PDF]

Energy Fuels
Crespo I, Cordero-Lanzac T, Cimiano A, Palos R, Gutiérrez A.   +4 more
europepmc   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source

Inflammatory pain in mice induces light cycle-dependent effects on sleep architecture. [PDF]

Neuropsychopharmacology
Burek DJ, Ibrahim KM, Hall AG, Sharma A, Cucinello-Ragland JA, Musiek ES, Morón JA, Carlezon WA.   +7 more
europepmc   +1 more source

Effects of light and phytochrome in heterotrophic growth of Lemna minor L.

, 1976
Axenic cultures of Lemna minor L. were grown on a medium containing sugars and amino acids. In continuous darkness the growth rate was one-tenth of the maximum in continuous light.
Rombach, J.
core  

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

Improved Eggshell Quality in Aged Hens Through Circadian Gut Microbiota and Metabolite Changes Induced by a 28-h Ahemeral Light Cycle. [PDF]

Animals (Basel)
Xu J, Li X, Liu X, Wu X, Fan Y, Yao Y, Zhang R, Wang D, Chen Y, Hao E, Sun Y, Chen J, Chen H, Shi L.   +13 more
europepmc   +1 more source

The Light-Speed Cycle Hypothesis

The Light-Speed Cycle Hypothesis, authored by Clinton Fisher in June 2025, proposes that the accelerating expansion of the universe is not heading toward heat death or eternal inflation, but toward a cyclical encounter with the light-speed boundary — the same condition that birthed the universe.
openaire   +2 more sources

Observations and modelling of the variability of the Solent-Southampton Water estuarine system

, 2008
Understanding the effect of physical forcing on estuarine functioning is of major importance to determine the rate of exchange of water, sediments, pollutants and nutrients between the continent and the ocean.
Levasseur, Anne
core  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source