Results 111 to 120 of about 295,338 (287)

Zirconia/phenylsiloxane nano-composite for LED encapsulation with high and stable light extraction efficiency. [PDF]

open access: yesRSC Adv, 2021
Lu Y   +11 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Enhanced light extraction by optimizing near-infrared perovskite-based light emitting diode (PeLED)

open access: yesScientific Reports
One of the outstanding optoelectronic devices is perovskite-based light emitting diodes (PeLEDs) that have diverse applications according to the wavelength of produced light.
Nava Tabibifar   +4 more
doaj   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Enhancing Light Extraction Efficiency in Micro-LEDs via Metal Photonic Crystals in the Passivation Layer and Air Photonic Crystals on the n-GaN Side

open access: yesIEEE Photonics Journal
Photonic crystals (PhCs), as a type of metamaterial, have attracted significant attention due to their ability to control light propagation to enhance the light extraction efficiency (LEE) of Micro-LEDs. However, the current advancements in improving the
Zhaoyong Liu   +4 more
doaj   +1 more source

Efficiency enhancement of InGaN amber MQWs using nanopillar structures

open access: yesNanophotonics, 2018
We have investigated the use of nanopillar structures on high indium content InGaN amber multiple quantum well (MQW) samples to enhance the emission efficiency. A significant emission enhancement was observed which can be attributed to the enhancement of
Ou Yiyu   +7 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

MgO nano-pyramids structure for enhancement of light extraction efficiency in vertical light-emitting diodes

open access: yes, 2019
We demonstrate novel method for improving light extraction efficiency for n-side-up vertical InGaN/GaN light-emitting diodes (V-LEDs) using MgO nano-pyramids and ZnO refractive-index modulation layer.
Lee, JL, Son, JH, Yu, HK
core   +1 more source

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