Results 101 to 110 of about 295,338 (287)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

Dendrimer light-emitting diodes

open access: yes, 2008
The electronics industry today is one that stands as a multi-billion dollar industry that is increasingly incorporating more and more products that have ever escalating applications in our everyday life.
Stevenson, Stuart G.
core  

Review Of the Light Extraction Efficiency of Gan Leds

open access: yesHighlights in Science, Engineering and Technology
Various new methods have emerged to enhance the light extraction efficiency (LEE) of Gallium Nitride (GaN)-based Light Emitting Diodes (LEDs),. This review examines several key techniques, including surface texturization, patterning of the GaN and substrate interface, chip geometry design, integration with photonic crystals, and epitaxial micro/nano ...
openaire   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Thickness-Dependent Performance of a Free-Standing Membrane LED

open access: yesIEEE Photonics Journal, 2015
We propose a free-standing membrane light-emitting diode (LED) on a GaN-on-silicon platform. Finite-difference time-domain (FDTD) simulation is used to investigate thickness-dependent performance of a free-standing membrane LED.
Xin Li   +8 more
doaj   +1 more source

Study on light extraction efficiency of a side-etched LED

open access: yesKorean Journal of Optics and Photonics, 2003
In the case of a AIGalnP/GaP system rectangular parallelepiped high brightness LED which has side walls etched to be slanted off the vertical direction, we have studied the effects of lossy electrodes and material absorption and etching depth and angle of side walls on its light extraction efficiency.
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Enhancing Light Extraction Efficiency of Vertical Emission of AlGaN Nanowire Light Emitting Diodes With Photonic Crystal

open access: yesIEEE Photonics Journal, 2019
AlGaN alloys have been widely used to make ultraviolet light-emitting diodes (UV-LEDs) because its energy bandgap covers 200–360 nm wavelength range.
Pengwei Du, Zhiyuan Cheng
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

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