Results 61 to 70 of about 10,092,068 (254)

MCNMF-Unet: a mixture Conv-MLP network with multi-scale features fusion Unet for medical image segmentation [PDF]

PeerJ Computer Science
Recently, the medical image segmentation scheme combining Vision Transformer (ViT) and multilayer perceptron (MLP) has been widely used. However, one of its disadvantages is that the feature fusion ability of different levels is weak and lacks flexible ...
Lei Yuan, Jianhua Song, Yazhuo Fan
doaj   +2 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Broadband and continuous wave pumped second-harmonic generation from microfiber coated with layered GaSe crystal

Opto-Electronic Advances, 2023
The conversion-efficiency for second-harmonic (SH) in optical fibers is significantly limited by extremely weak second-order nonlinearity of fused silica, and pulse pump lasers with high peak power are widely employed.
Zhen Hao, Biqiang Jiang, Yuxin Ma, Ruixuan Yi, Xuetao Gan, Jianlin Zhao   +5 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Fano resonance from a one-dimensional topological photonic crystal

APL Photonics, 2021
An ultra-compact one-dimensional topological photonic crystal (1D-TPC) is designed in a single mode silicon bus-waveguide to generate the Fano resonance lineshape.
Linpeng Gu, Binbin Wang, Qingchen Yuan, Liang Fang, Qiang Zhao, Xuetao Gan, Jianlin Zhao   +6 more
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

THE INFLUENCE OF POINT MEASURING INSTRUMENT THE FIELD OF WORK ON THE METHOD SPLI FLUX AGAINTS QUANTITY DAYLIGHT IN RS AND RSS [PDF]

, 2017
RSS and RS are houses with minimal covering so quantity daylight that enters into a chamber having the window also at least .Daylight are needed in a house or building to reduce its use of the light on the day .Windows or openings on house or building a ...
Ummul Latifa, Zuraida
core   +1 more source

Pressure-Dependent Structural, Electronic, Mechanical, and Optical Properties of Cs₂SeCl₆: A DFT Simulation

Chemistry
Based on density functional theory, the structural, mechanical, and photoelectric properties of the perovskite material Cs2SeCl6 were systematically studied under pressures ranging from 0 to 50 GPa.
Na Dong, Yiping Pang, Shuai Xue, Jing Wang, Jiancai Leng, Chuanfu Cheng, Hong Ma   +6 more
doaj   +1 more source

Dynamically reparameterized light fields [PDF]

Proceedings of the 27th annual conference on Computer graphics and interactive techniques - SIGGRAPH '00, 2000
This research further develops the light field and lumigraph image-based rendering methods and extends their utility. We present alternate parameterizations that permit 1) interactive rendering of moderately sampled light fields of scenes with significant, unknown depth variation and 2) low-cost, passive autostereoscopic viewing.
Aaron Isaksen, Leonard McMillan, Steven J. Gortler   +2 more
openaire   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source