Results 51 to 60 of about 1,606,955 (297)

Automated staging of zebrafish embryos with deep learning

open access: yesLife Science Alliance
Introducing KimmelNet: A deep learning model that accurately stages populations of zebrafish embryos from 2D brightfield images, offering a rapid and objective alternative to manual observations.
Rebecca A Jones   +2 more
doaj   +1 more source

Novel type of pilus associated with a Shiga-toxigenic E. coli hybrid pathovar conveys aggregative adherence and bacterial virulence

open access: yesEmerging Microbes and Infections, 2018
A large German outbreak in 2011 was caused by a locus of enterocyte effacement (LEE)-negative enterohemorrhagic E. coli (EHEC) strain of the serotype O104:H4. This strain harbors markers that are characteristic of both EHEC and enteroaggregative E. coli (
Christina Lang   +6 more
doaj   +1 more source

The large extracellular loop of CD63 interacts with gp41 of HIV-1 and is essential for establishing the virological synapse

open access: yesScientific Reports, 2021
Human immunodeficiency virus type 1 (HIV-1) persists lifelong in infected individuals and has evolved unique strategies in order to evade the immune system. One of these strategies is the direct cell-to-cell spread of HIV-1.
Daniel Ivanusic   +3 more
doaj   +1 more source

Strength of interactions in the Notch gene regulatory network determines patterning and fate in the notochord

open access: yeseLife, 2022
Development of multicellular organisms requires the generation of gene expression patterns that determines cell fate and organ shape. Groups of genetic interactions known as Gene Regulatory Networks (GRNs) play a key role in the generation of such ...
Héctor Sánchez-Iranzo   +2 more
doaj   +1 more source

Multiple scattering limit in optical microscopy

open access: yes, 2017
Optical microscopy offers a unique insight of biological structures with a sub-micrometer resolution and a minimum invasiveness. However, the inhomogeneities of the specimen itself can induce multiple scattering of light and optical aberrations which ...
Aubry, Alexandre   +4 more
core   +1 more source

Hyperspectral light sheet microscopy [PDF]

open access: yesNature Communications, 2015
AbstractTo study the development and interactions of cells and tissues, multiple fluorescent markers need to be imaged efficiently in a single living organism. Instead of acquiring individual colours sequentially with filters, we created a platform based on line-scanning light sheet microscopy to record the entire spectrum for each pixel in a three ...
Wiebke Jahr   +4 more
openaire   +4 more sources

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Printed Lateral p–n Junction for Thermoelectric Generation

open access: yesSmall Science
Printed thermoelectric generators (TEGs) show promising potential for converting waste heat into useful electricity at a low cost but fall short of exhibiting a conversion efficiency anticipated from materials’ properties.
Md Mofasser Mallick   +6 more
doaj   +1 more source

High-extinction VIPA-based Brillouin spectroscopy of turbid biological media

open access: yes, 2016
Brillouin microscopy has recently emerged as powerful technique to characterize the mechanical properties of biological tissue, cell and biomaterials.
Fiore, Antonio   +4 more
core   +1 more source

An integrative description of a population of Mesobiotus radiatus (Pilato, Binda & Catanzaro, 1991) from Kenya [PDF]

open access: yes, 2018
In a moss sample collected from Mount Kulal in Kenya, a new population of Mesobiotus radiatus was found. Given that the original description of M. radiatus was based solely on the morphology observed by light microscopy and measurements based mostly on a
Kaczmarek, Łukasz   +3 more
core   +1 more source

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