Results 91 to 100 of about 10,427,001 (301)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

A Wiener process–based remaining life prediction method for light-emitting diode driving power in rail vehicle carriage

open access: yesAdvances in Mechanical Engineering, 2019
Remaining life prediction is an effective way to optimize maintenance strategy and improve service life for light-emitting diode driving power in rail vehicle carriage.
Zhi Gao   +4 more
doaj   +1 more source

Spring Street Station photograph

open access: yes, 1905
Taken between 1905 and 1930, this photograph shows the electric railway station on Spring Street in Columbus, Ohio, bordering the Scioto River. This photograph is part of the Columbus Railway, Power, and Light Company collection, consisting of 53 glass ...
Columbus Railway, Power and Light Company (Columbus, Ohio); Columbus Railway and Light Company
core  

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

Continuous-wave laser emission of 10.4 W, 4.16 μm from HBr-filled hollow-core fiber

open access: yesHigh Power Laser Science and Engineering
We report here the characteristics of a high-power continuous-wave mid-infrared (mid-IR) fiber light source based on nested anti-resonant hollow-core fiber (AR-HCF) filled with HBr gas.
Qi Chen   +12 more
doaj   +1 more source

Reduksi Osilasi Daya Pada MPPT Panel Surya Dengan Metode Kombinasi PNO dan Fuzzy

open access: yesJurnal Rekayasa Elektrika, 2019
Solar panels are an essential part of a system of electrical source devices that receives light energy to be processed into electrical energy with direct current (DC) output.
Suriadi Suriadi   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Toward 100‐Watt‐Level Mid‐Infrared Supercontinuum Light Generation

open access: yesAdvanced Photonics Research
The applications of mid‐infrared supercontinuum (SC) light sources are currently being extended to various fields. However, the difficulties (including thermal limitation, optical damage, and chemical stability) in increasing their output power to 100 ...
Qian Zhang   +9 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

open access: yesFEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea   +5 more
wiley   +1 more source

Coupled piezoelectric-circuit FEA to study influence of a resistive load on power output of piezoelectric energy devices [PDF]

open access: yes, 2009
This paper presents, for the first time, a coupled piezoelectric-circuit finite element model (CPC-FEM) to analyze the power output of vibration-based piezoelectric energy harvesting devices (EHDs) when connected to a resistive load.
Zhu, Meiling   +5 more
core   +1 more source

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