Results 141 to 150 of about 1,325,509 (262)

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Light Quality Potentiates the Antioxidant Properties of Brassica rapa Microgreen Extracts against Oxidative Stress and DNA Damage in Human Cells. [PDF]

Antioxidants (Basel), 2023
Paolillo I, Costanzo G, Delicato A, Villano F, Arena C, Calabrò V.   +5 more
europepmc   +1 more source

Work with quality light [PDF]

British Dental Journal, 2009
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Light-Quality-Dependent Greening and Steroidal Glycoalkaloid Accumulation in Potato Tubers: Regulatory Mechanisms and Postharvest Strategies to Reduce Food Safety Risks. [PDF]

Foods
Sa G, Zao X, Yuan J, Cheng L, Yu B.
europepmc   +1 more source

Growth Light Quality Influences Leaf Surface Temperature by Regulating the Rate of Non-Photochemical Quenching Thermal Dissipation and Stomatal Conductance. [PDF]

Int J Mol Sci, 2023
Trojak M, Skowron E.
europepmc   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

Effects of Light Quality and Photoperiod on Growth, Dry Matter Production and Yield of Ginger. [PDF]

Plants (Basel)
Zhang H, Li X, Han T, Huang Q, Liu J, Tian A, Liu L, Sun G, Dong L, Wang H, Xie X, Peng S, Li Q, Li H.   +13 more
europepmc   +1 more source

Effect of Light Quality on Metabolomic, Ionomic, and Transcriptomic Profiles in Tomato Fruit. [PDF]

Int J Mol Sci, 2022
Xiao L, Shibuya T, Watanabe T, Kato K, Kanayama Y.   +4 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source