Results 71 to 80 of about 5,326,889 (255)

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

Light scattering and nanoparticles

open access: yesMaterials Today, 2009
Metal oxide nanoparticles are finding increasing application in the preparation of new nanocrystalline materials, with metal oxide composites being used to confer new electronic, magnetic and optical properties into material structures. Often these materials are formulated and processed as slurries or aqueous suspensions.
Ana Morfesis, Ulf Nobbmann
openaire   +2 more sources

Characterization of anisotropic nano-particles by using depolarized dynamic light scattering in the near field

open access: yes, 2009
Light scattering techniques are widely used in many fields of condensed and sof t matter physics. Usually these methods are based on the study of the scattered light in the far field.
A. P. Philipse   +30 more
core   +1 more source

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

Quantum imaging of spin states in optical lattices

open access: yes, 2010
We investigate imaging of the spatial spin distribution of atoms in optical lattices using non-resonant light scattering. We demonstrate how scattering spatially correlated light from the atoms can result in spin state images with enhanced spatial ...
D. N. Klyshko   +2 more
core   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

open access: yesMolecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song   +11 more
wiley   +1 more source

Inelastic electron and light scattering from the elementary electronic excitations in quantum wells: Zero magnetic field

open access: yes, 2012
The most fundamental approach to an understanding of electronic, optical, and transport phenomena which the condensed matter physics (of conventional as well as nonconventional systems) offers is generally founded on two experiments: the inelastic ...
Kushwaha, Manvir S.
core   +2 more sources

Understanding and measuring mechanical signals in the tumor stroma

open access: yesFEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz   +3 more
wiley   +1 more source

Micro-focused Brillouin light scattering: imaging spin waves at the nanoscale

open access: yesFrontiers of Physics, 2015
Spin waves constitute an important part of research in the field of magnetization dynamics. Spin waves are the elementary excitations of the spin system in a magnetically ordered material state and magnons are their quasi particles.
T. Sebastian   +4 more
semanticscholar   +1 more source

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