Results 71 to 80 of about 260,963 (291)

Twelve‐month change in quantitative MRI calf muscle fat fraction in CMT1A predicts clinical change over 4 years

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective We measured clinical and quantitative MRI outcome measures in CMT1A to assess long‐term responsiveness, establish longitudinal validity and assess MRI as a bridging biomarker. Methods Twenty patients with CMT1A and 20 matched controls underwent MRI, myometry and clinical assessments up to four times over mean 4‐year follow‐up ...
Matthew R. B. Evans, Hamza A. Salhab, Christopher D. J. Sinclair, Sachit Shah, Michael G. Hanna, Tarek A. Yousry, John S. Thornton, Jasper M. Morrow, Mary M. Reilly   +8 more
wiley   +1 more source

ALS plasma biomarkers reveal neurofilament and pTau correlate with disease onset and progression

Annals of Clinical and Translational Neurology, EarlyView.
Abstract Objective We performed a pilot screen to assess the utility of the NULISA™ (Nucleic‐acid‐Linked Immuno‐Sandwich Assay) platform in the identification of amyotrophic lateral sclerosis (ALS) biomarkers. Methods Plasma from 86 individuals (48 ALS, 18 asymptomatic C9orf72 repeat expansion carriers (AsymC9), and 20 healthy controls) was analyzed ...
Eleanor V. Thomas, Changee Han, Woo Jae Kim, Seneshaw Asress, Yingjie Li, Jennifer A. Taylor, Marla Gearing, Christina N. Fournier, Zachary T. McEachin, Nicholas T. Seyfried, Jonathan D. Glass   +10 more
wiley   +1 more source

CSF Tau Is a Biomarker of Hippocampal Injury in Cryptogenic New‐Onset Refractory Status Epilepticus

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cryptogenic new‐onset refractory status epilepticus (cNORSE) is a devastating condition characterized by the de novo onset of status epilepticus with unclear etiology. The identification of relevant early biomarkers in cNORSE is important to elucidate pathophysiology, aid clinical decision‐making, and prognosticate outcomes in cNORSE.
Yihui Goh, Yoonhyuk Jang, Soo Jean Shin, Soo Hyun Ahn, Su Yee Mon, Yoon Hee Shin, Kon Chu, Sang Kun Lee, Soon‐Tae Lee   +8 more
wiley   +1 more source

Light WIMP Searches Involving Electron Scattering

Advances in High Energy Physics, 2018
In the present work we examine the possibility of detecting electrons in light dark matter searches. These detectors are considered to be the most appropriate for detecting dark matter particles with a mass in the MeV region.
J. D. Vergados, Ch. C. Moustakidis, Yeuk-Kwan E. Cheung, H. Ejiri, Yeongduk Kim, Jeong-Yeon Lee   +5 more
doaj   +1 more source

Tissue Optics and Photonics: Light-Tissue Interaction

Journal of Biomedical Photonics & Engineering, 2015
This is the second section of the review-tutorial paper describing fundamentals of tissue optics and photonics. As the first section of the paper was mostly devoted to description of biological tissue structures and their specificity related to ...
Valery V. Tuchin
doaj   +1 more source

Artificial Receptor in Synthetic Cells Performs Transmembrane Activation of Proteolysis

Advanced Biology, EarlyView.
Transmembrane signaling is the hallmark of living cells and is among the highest challenges for the design of synthetic cells. Herein, an artificial receptor based on the chemistry of self‐immolative linkers is used to communicate information across the lipid bilayer, for transmembrane activation of enzymatic activity. Abstract The design of artificial,
Ane Bretschneider Søgaard, Kaja Borup Løvschall, Mireia Casanovas Montasell, Clara Bakkegaard Cramer, Pere Monge Marcet, Andreas Bøtker Pedersen, Josefine Hammer Jakobsen, Alexander N. Zelikin   +7 more
wiley   +1 more source

Experimental identification of unique angular dependent scattering behavior of nanoparticles

Journal of the European Optical Society-Rapid Publications, 2017
Background Nanoparticles exhibit unique light scattering properties and are applied in many research fields. Methods In this work, we perform angular resolved scattering measurements to study the scattering behaviour of random and periodic silver (Ag ...
Guanchao Yin, Min Song, Waseem Raja, Patrick Andrae, Martina Schmid   +4 more
doaj   +1 more source

Elucidating the Supramolecular Interaction of Positively Supercharged Fluorescent Protein with Anionic Phthalocyanines

Advanced Biology, EarlyView.
Positively supercharged mGreenLatern protein is self‐assembled electrostatically with negatively charged zinc phthalocyanines to yield bio‐based photoactive materials in aqueous media. The addition of phthalocyanines results in the formation of large complexes fully quenching of the protein fluorescence. The results indicate an energy transfer from the
Sharon Saarinen, Ramsha Khan, Marta Patrian, Juan Pablo Fuenzalida‐Werner, Rubén D. Costa, Petr Zimcik, Veronika Novakova, Tero‐Petri Ruoko, Nikolai V. Tkachenko, Eduardo Anaya‐Plaza, Mauri A. Kostiainen   +10 more
wiley   +1 more source

1.5-multiplicity molecular light scattering in fluids?

Condensed Matter Physics, 2006
The third-order thermodynamic moment of the density fluctuations is shown to contribute notably to the molecular light scattering in a single-component fluid.
M.Ya.Sushko
doaj   +1 more source

Research of detection technology of metal dust concentratio

Gong-kuang zidonghua, 2017
For problem that weighing method cannot realize real-time and on-line detection for metal dust concentration, basic principle of light scattering method and charge induction method for metal dust concentration detection were analyzed, and signal ...
ZHANG Suorong, CHEN Jiange
doaj   +1 more source