Results 71 to 80 of about 4,134,739 (261)

Negative Regulation of FGFR (Fibroblast Growth Factor Receptor) Signaling

, 2021
FGFR (fibroblast growth factor receptor) signaling controls fundamental processes in embryonic, fetal and adult human life. The magnitude, duration, and location of FGFR signaling must be strictly controlled in order to induce the correct biological ...
Wiedlocha, Antoni, Jørgen Wesche, Szybowska, Patrycja Maria, Michal Kostas, Antoni Wiedlocha, Patrycja Szybowska, Kostas, Michal Janusz, Wesche, Jørgen, Haugsten, Ellen Margrethe, Ellen Margrethe Haugsten   +9 more
core   +1 more source

Light-Mediated Signaling and Metabolic Changes Coordinate Stomatal Opening and Closure

Frontiers in Plant Science, 2020
Stomata are valves on the leaf surface controlling carbon dioxide (CO2) influx for photosynthesis and water loss by transpiration. Thus, plants have to evolve elaborate mechanisms controlling stomatal aperture to allow efficient photosynthesis while ...
Juan Yang, Chunlian Li, Dexin Kong, Fangyan Guo, Hongbin Wei, Hongbin Wei   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Fibroblast Growth Factor Receptor Signaling in Skin Cancers

, 2019
Fibroblast growth factor (FGF)/Fibroblast growth factor receptor (FGFR) signaling regulates various cellular processes during the embryonic development and in the adult organism.
Malgorzata Czyz
core   +1 more source

TGFbeta/BMP Signaling Pathway in Cartilage Homeostasis [PDF]

, 2019
Contains fulltext : 208575.pdf (Publisher’s version ) (Open Access)Cartilage homeostasis is governed by articular chondrocytes via their ability to modulate extracellular matrix production and degradation.
Caam, A.P.M. van, Thielen, N.G.M., Peter van der Kraan, Nathalie Thielen, Arjan van Caam, Kraan, P.M. van der   +5 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Signaling pathways for transduction of the initial message of the glycocode into cellular responses [PDF]

, 1998
The sugar units of glycan structures store information and establish an alphabet of life. The language of the oligosaccharide coding units is deciphered by receptors such as lectins and the decoded message can be transduced by multiple signaling pathways.
Gabius, Hans-Joachim, Villalobo, Antonio, Villalobo, A.   +2 more
core   +1 more source

Intermittent Supplementation with Far-Red Light Accelerates Leaf and Bud Development and Increases Yield in Lettuce

Plants
Supplementation with far-red light in controlled environment agriculture production can enhance yield by triggering the shade avoidance syndrome. However, the effectiveness of this yield enhancement can be further improved through intermittent far-red ...
Yanke Liu, Rong Ye, Xinying Gao, Rongcheng Lin, Yang Li   +4 more
doaj   +1 more source

Photoreceptor Mediated Plant Growth Responses: Implications for Photoreceptor Engineering toward Improved Performance in Crops

Frontiers in Plant Science, 2017
Rising temperatures during growing seasons coupled with altered precipitation rates presents a challenging task of improving crop productivity for overcoming such altered weather patterns and cater to a growing population.
Ophilia I. L. Mawphlang, Eros V. Kharshiing   +1 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source