Results 51 to 60 of about 86,355 (260)

Unraveling 4‐Phenylbutyrate's Therapeutic Role in SLC6A1 Disorders: Pharmacochaperoning Over HDAC Inhibition

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw   +5 more
wiley   +1 more source

Effects of Infrared Optical Trapping on Saccharomyces cerevisiae in a Microfluidic System

open access: yesSensors, 2017
Baker’s yeast (Saccharomyces cerevisiae) represents a very popular single-celled eukaryotic model organism which has been studied extensively by various methods and whose genome has been completely sequenced.
Zdeněk Pilát   +3 more
doaj   +1 more source

Thermodynamic Pathways of Nonequilibrium Solidification in Wire‐Arc Additive Manufacturing Fe‐Based Multicomponent Alloy Structures

open access: yesAdvanced Engineering Materials, EarlyView.
Geometry‐driven thermal behavior in wire‐arc additive manufacturing (WAAM) influences microstructural evolution during nonequilibrium solidification of a chemically complex Fe–Cr–Nb–W–Mo–C nanocomposite system. By comparing different deposits configurations, distinct entropy–cooling rate correlations, segregation, and carbide evolution are revealed ...
Blanca Palacios   +5 more
wiley   +1 more source

Near-resonant light scattering by an atom in a state-dependent trap

open access: yesNew Journal of Physics
There are an increasing number of experimental scenarios where near-resonant light is applied to atoms tightly trapped in far off-resonant optical fields, such as for quantum optics applications or for atom imaging.
T D Karanikolaou, R J Bettles, D E Chang
doaj   +1 more source

Low‐Angle Grain Boundaries and Re‐Segregation in Single‐Crystalline Ni‐Base Superalloys

open access: yesAdvanced Engineering Materials, EarlyView.
This work demonstrates that Re‐segregation at low‐angle grain boundaries (LAGBs) in Ni‐base superalloys is influenced by misorientation angle. Advanced microscopy and atom probe tomography reveal that higher misorientation angles increases Re‐segregation.
Alireza B. Parsa   +9 more
wiley   +1 more source

Time‐Dependent Oxidation and Scale Evolution of a Wrought Co/Ni‐Based Superalloy

open access: yesAdvanced Engineering Materials, EarlyView.
This study shows how a new wrought Co/Ni‐based superalloy resists oxidation at 800 ∘$^\circ$C. The oxide scale changes from rough, fast‐growing spinel to a dense, protective chromia–alumina layer. Atom probe analysis reveals tiny refractory‐rich bubbles at the interface that mark the transition to long‐term, diffusion‐controlled protection ...
Cameron Crabb   +6 more
wiley   +1 more source

Trapping light, revealing properties: Laser trapping as a powerful tool for photoluminescence spectroscopy

open access: yesChemical Physics Impact
Laser trapping, a non-contact technique for manipulating microscopic objects, has gained prominence in scientific research. When coupled with fluorescence spectroscopy, it offers a powerful tool for exploring material properties.
Dr. Md. Jahidul Islam   +3 more
doaj   +1 more source

New data on the distribution of Pericyma albidentaria Freyer, 1842 (Lepidoptera, Erebidae) in Uzbekistan [PDF]

open access: yesCheck List
We present new data on the distribution of Pericyma albidentaria Freyer, 1842 (Lepidoptera, Erebidae) based on voucher-confirmed material from the Fergana Valley in Uzbekistan.
Islomjon Zokirov   +5 more
doaj   +3 more sources

The Collapsible Light Trap: a portable Pennsylvania Light Trap for collecting aquatic insects

open access: yesAnais da Academia Brasileira de Ciências
A Collapsible Light Trap (CLT) for collecting insects, particularly aquatic insects, is described here. CLT is a modified Pennsylvania Light Trap with the advantage of being collapsible and lightweight to be carried in a small backpack and very easy to set up in the field.
JORGE LUIZ NESSIMIAN   +5 more
openaire   +4 more sources

Modular Critical Element Recycling Platform Using a Nanoporous Additively Manufactured Gyroid

open access: yesAdvanced Engineering Materials, EarlyView.
A modular recycling platform integrates 3D‐printed nanoporous gyroid structures to enable efficient critical element recovery. This system utilizes a hierarchical architecture, combining macroscopic channels with polymerization‐induced nanoscale porosity. By systematically tuning structural wall thickness and resin formulation, the platform achieves an
Xiangyu Gao   +6 more
wiley   +1 more source

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