Results 71 to 80 of about 5,756,769 (295)

Challenges for dark matter direct search with SiPMs

open access: yesFrontiers in Physics
Liquid xenon and liquid argon detectors are leading the direct dark matter search and are expected to be the candidate technology for the forthcoming generation of ultra-sensitive large-mass detectors.
Alessandro Razeto, Nicola Rossi
doaj   +1 more source

Grain production and assimilate utilization of wheat in relation to cultivar characteristics, climatic factors and nitrogen supply [PDF]

open access: yes, 1978
The effects on grain production of cultivar characteristics, nitrogen supply and some climatic factors were studied in field trials and under controlled environmental conditions.
Spiertz, J.H.J.
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Effects of light leaf spot (Pyrenopeziza brassicae ) on yield of winter oilseed rape (Brassica napus )

open access: yes, 1998
The relationship between development of light leaf spot and yield loss in winter oilseed rape was analysed, initially using data from three experiments at sites near Aberdeen in Scotland in the seasons 1991/92, 1992/93 and 1993/94, respectively. Over the
Fitt, B. D. L.   +7 more
core   +1 more source

Visible-Light-Mediated StadlerZiegler Arylation of Thiosugars with Anilines

open access: yes, 2022
Here, we report a one-pot Stadler–Ziegler reaction toward the synthesis of 1-thioglycosides in good yield from commercially available anilines and (un)­protected 1-glycosyl thiols. This simple and mild approach employs the photoredox catalyst [Ru­(bpy)3]­
Samir Messaoudi   +5 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Modelling the impacts of in-field soil and irrigation variability on onion yield [PDF]

open access: yes, 2013
Globally, onion (Allium cepa L.) represents an extremely important crop in terms of production, value and consumption. Similarly, in the UK onion production is considered to be one of the most important high-value field vegetables, with ca.
Perez Ortola, Marta
core   +4 more sources

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