Results 91 to 100 of about 13,884,188 (359)
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
, 2012 Without light, interior architecture cannot be fully designed and experienced. It is one of the key tools for an interior designer, but can be a dauntingly technical subject for students.
Innes, Malcolm
core
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
, 2009 A study was conducted at Jönköping University in 2008 to investigate how a group of 20 people would be affected by spending an entire day in a total of three different lighting environments.
Säter, Monica
core
Laser Technik Journal, 2017 AbstractTucked away behind the glass facade of Trumpf headquarters is a brain‐storming room used by an additive manufacturing team. This is where they craft strategies and opportunities to make this promising technology more productive and to extend its appeal to a broader user base.
openaire +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Luminous Color in Architecture: Exploring Methodologies for Design-Relevant Research
Enquiry: The ARCC Journal of Architectural Research, 2015 This paper describes our process in conducting research toward better understanding of the experience and perception of luminous colors in architectural contexts. Our intention is to contribute to a body of knowledge useful for designers by introducing a
Ute Christa Besenecker, Ted Krueger
doaj +1 more source
IOP Conference Series: Materials Science and Engineering, 2018 The lighting design of exhibition space has a great impact on visual and colour perception and different lighting arrangements can create very different visual impression of artworks and, if not carefully designed, compromise the enjoyment of the viewers.
F. Leccese +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source