Results 101 to 110 of about 9,388,892 (203)

Assessing the Accuracy of Multispectral Simulation Tools for Predicting Non-Visual Lighting Metrics in Sports Hall Building

open access: yesJournal of Daylighting
Sports hall buildings are widely utilized as fitness facilities where the occupants can engage in physical activities to promote their health and well-being.
Tiara Nurhuda   +6 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Drawing in architectural lighting design

open access: yes, 2011
Drawing is an important tool for lighting designers. Not only as a means of visual communication but also to aid visual thinking. As a process and product, drawing is a constituent part of the overall lighting design process, from concept to realisation.
Skipetari, A.   +3 more
core   +1 more source

Generative Lighting Design with Synesthesia [PDF]

open access: yes, 2020
Et system til audiovisuelle oplevelser er udviklet med inspiration fra den menneskelige neurofysiologiske tilstand synestesi. Forskning tyder på, at synestesi kan være resultatet af en neural kortslutning mellem sensoriske systemer i hjernen, hvilket ...
Tyroll, Simon Borst
core  

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Exploring the Interaction Mechanism of Mediated Space from the Perspective of the Spatial Organism

open access: yesBuildings
Driven by advances in artificial intelligence, immersive technologies, and related digital innovations, public cultural spaces are undergoing significant mediatization.
Xinyuan Cai, Kang Wang, Jian Zhang
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

An outlook for integrating lighting design into currently used stylobate structures

open access: yesАрхитектон
Engineering solutions that embody the key conceptual directions for integrating outdoor lighting into combined stylobate structures have been considered.
Kavtoreva Ekaterina S.   +2 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

open access: yesMolecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Work place lighting in foundries

open access: yes, 1979
An analysis of work processes and lighting conditions in Swedish foundries with a recommendation for improving the lighting for workers in manual casting is presented.
Carlsson, Lars   +3 more
core  

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