Results 121 to 130 of about 13,884,188 (359)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Performance Lighting Design: How to Light for the Stage, Concerts and Live Events

open access: yes, 2018
A practical guide to the art and technique of lighting for the stage, this book explains the complex mixture of craft, collaboration and creativity behind successful lighting design.
Moran, Nick
core  

Light design in children's play environment

open access: yesАрхитектон
The article offers a review of domestic and foreign experiences in lighting design of children's playgrounds. The need to study this topic is due to the lack of clear differentiation of lighting equipment for children's play environments.
Belova Marina V.
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Design considerations for interactive office lighting interface characteristics, shared and hybrid control

open access: yes, 2019
The inclusion of IoT in office lighting allows people to have personal lighting control at their workplace. To design lighting control interfaces that fit people’s everyday living, we need a better understanding of how people experience lighting ...
Werff, TCF Thomas van de   +12 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Generative Lighting Design with Synesthesia

open access: yes, 2020
Et system til audiovisuelle oplevelser er udviklet med inspiration fra den menneskelige neurofysiologiske tilstand synestesi. Forskning tyder på, at synestesi kan være resultatet af en neural kortslutning mellem sensoriske systemer i hjernen, hvilket ...
Tyroll, Simon Borst
core  

An Architectural Solution to a Biological Problem: A Systematic Review of Lighting Designs in Healthcare Environments

open access: yesApplied Sciences
Neuroscience and biological evidence emphasizes the profound influence of natural light on human health, offering benefits such as reducing fatigue, heightened alertness in healthcare providers, and improving patient outcomes.
Seyedeh Nazli Hosseini   +4 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

LIGHTING DESIGN FOR THE AGING EYES

open access: yes, 2017
Lighting allows users to accomplish their tasks, feel safe and understand the surrounding environment. Therefore, it is an inseparable component of buildings. Building codes, energy standards and regulations determine the required illuminances to provide
Arzu Cılasun Kunduracı
semanticscholar   +1 more source

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