Results 181 to 190 of about 13,884,188 (359)
An ipRGC-influenced/Non-Visual Spectral Occupant Model for lighting design, Part 2: Photobiological model implementation. [PDF]
Light Res TechnolJakubiec JA, Alight A.
europepmc +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Guide for optimizing the effectiveness and the efficiency of roadway lighting. [PDF]
Contract No. 21151The objective of the present project was to develop a simple guide for roadway lighting replacementapproaches using new light source technologies to maintain visibility for safety, while reducing energy use.Several roadway types were ...
Bullough, J. D. +1 more
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An ipRGC-influenced/Non-Visual Spectral Occupant Model (iNSOM) for lighting design, Part 1: Light simulation method. [PDF]
Light Res TechnolAlight A, Jakubiec JA.
europepmc +1 more source
YIPFα1A expression is regulated by multilayered molecular mechanisms
FEBS Open Bio, EarlyView.YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji +2 more
wiley +1 more source
Lighting design for institutionalized people with dementia symptoms
, 2011 The number of people suffering from dementia is estimated at around 24 million and will rise to 81 million at the year 2040. Behavioural (eg restlessness at night) and psychological symptoms mostly lead to the situation where people are no longer able to
Schoutens, A.M.C. +4 more
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Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong +3 more
wiley +1 more source
This thesis investigates how lighting can be used as a design toolto transform underutilized public spaces into socially vibrant,emotionally resonant environments after dark. Focusing on BellaPark in Ørestad, Copenhagen, the study explores how theabsence
Gomez Palacios, Francisca
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