Results 51 to 60 of about 6,945,171 (251)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Performance of different colour quality metrics proposed to CIE TC 1-91 [PDF]

, 2017
The main aim of the article is to find out the performance of different metrics proposed to CIE TC 1-91. Currently, six different indexes have been proposed to CIE TC 1-91: Colour Quality Scale (CQS), Feeling of Contrast Index (FCI), Memory colour ...
Dangol, R., Rajendra Dangol, Dangol, Rajendra, Dangol, R, Bhusal, Pramod, Bhusal, P., Pramod Bhusal   +6 more
core   +2 more sources

Assessment of lighting quality in urban outdoor sports fields using 10-m SDGSAT-1 nighttime light imagery

International Journal of Applied Earth Observations and Geoinformation
As public awareness of health and well-being grows, the demand for sufficient and well-functioning outdoor sports fields (OSFs) has increased. A high-quality lighting environment at these sites, characterized by sufficient brightness and appropriate ...
Tingrui Guo, Min Zhao, Zhuolin Tao, Jiaqi Fu, Xinyi Song, Yuyu Zhou   +5 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Energy efficiency and colour quality improvement and subjective preference of LED office lighting [PDF]

, 2016
The objectives of this thesis were to explore different approaches to improve energy efficiency and colour quality, and to find out the subjective preference of LED office lighting. Four approaches (optimization of LED spectra, lighting retrofitting, hue-
Baniya, Rupak Raj
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The Influence of Lighting on The Bedroom Towards The Sleep Quality of Children Aged 0-5 Years

Physics Communication
Lighting in the bedroom is important in maintaining the quality of children's sleep. At the age of 0-5 years, a child has a sleep duration of around 11-18 hours, so it is necessary to pay attention to the lighting in the bedroom so that children have ...
Risnawati Uding, Fianti Fianti, Ian Yulianti   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

A review of the lighting performance in buildings through energy efficiency [PDF]

, 2014
As developing countries including Malaysia, are now moving towards sustainable development is in line with the Ninth Malaysia Plan, 9th MP, the development should be built to meet current and future needs for achieving sustainability of economic ...
Kamaruzzaman, S.N, Zulkifli, Nursyahida
core   +1 more source

Quantitative Evaluation and Optimization of the Light Environment in Sleep-Conducive Workplaces

Buildings
Sleep is an essential physiological process, and residential lighting environments significantly impact sleep quality. To address circadian phase delays exacerbated by pre-sleep smartphone use in youth, this study developed targeted lighting ...
Baogang Zhang, Fei Xu, Ming Liu, Ruicong Li, Kehui Zhao   +4 more
doaj   +1 more source