Results 61 to 70 of about 6,945,171 (251)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Energy-neutral solar-powered street lighting with predictive and adaptive behaviour [PDF]
, 2014 Street lighting can enhance the safety and security of residential and commercial areas. However, its installation and operation is expensive: cables must be installed, and power is drawn from the grid which is typically dominated by non-renewable ...
Geoff V. Merrett +7 more
core +1 more source
Ambiente ConstruídoAlém do aproveitamento da iluminação natural, indicado como um fator primordial na economia de energia das edificações, o posicionamento das luminárias bem como de suas especificações pode contribuir para o conforto ambiental e a conservação de energia ...
Letícia Niero Moraes, Anderson Claro
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
, 1928 Colored catalog intended for customers purchasing lighting fixtures from the Acme Lighting Products company.Cover title.
Acme Lighting Products
core
Evaluation of energy-efficiency in lighting systems using sensor networks [PDF]
, 2009 Paper presented at Buildsys: First ACM Workshop On Embedded Sensing Systems For Energy-Efficiency In Buildings, 3 Nov, Berkeley, USAIn modern energy aware buildings, lighting control systems are put in place so to maximise the energy-efficiency of the ...
O'Hare, G. M. P. (Greg M. P.) +2 more
core +2 more sources
A Survey on the Intensity of Lighting in Elementary Schools of Bojnurd City
بهداشت کار و ارتقای سلامت, 2022 Background and Aim: Optimal lighting should create a balance between economy and the environment. In order to comply with safety and health principles of the staff, proper lighting of the work environment should be provided for everyday tasks ...
Faeze SEPAHI ZOERAM +3 more
doaj
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source