Results 81 to 90 of about 87,316 (308)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Evaluating the Quality of Light Emitted by Smartphone Displays

Applied Sciences
The increased use of smartphones in daily life challenges researchers regarding the quality of light emitted by screens. This study aims to analyze displays’ qualitative and quantitative light parameters from various smartphone models available on the ...
Nina Piechota, Krzysztof Skarżyński, Kamil Kubiak   +2 more
doaj   +1 more source

Phosphor-Free Three-Dimensional Hybrid White LED With High Color-Rendering Index

IEEE Photonics Journal, 2019
In this study, we demonstrate the phosphor-free hybrid white LED devices with the combination of the truncated-hexagonal-pyramid (THP) structures and quantum dots (QDs) (THPQD).
Jie Zhao, Tongbo Wei, Ji Zhang, Yonghui Zhang, Xuecheng Wei, Jianchang Yan, Junxi Wang, Jinmin Li   +7 more
doaj   +1 more source

Structural phase transitions and photoluminescence mechanism in a layer of 3D hybrid perovskite nanocrystals

AIP Advances, 2020
Although structural phase transitions in single-crystal hybrid methyl-ammonium (MA) lead halide perovskites (MAPbX3, X = Cl, Br, I) as a function of temperature are common phenomena, they have never been observed in the corresponding nanocrystals.
Yuri D. Glinka, Rui Cai, Xian Gao, Dan Wu, Rui Chen, Xiao Wei Sun   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Performance of different colour quality metrics proposed to CIE TC 1-91

, 2017
The main aim of the article is to find out the performance of different metrics proposed to CIE TC 1-91. Currently, six different indexes have been proposed to CIE TC 1-91: Colour Quality Scale (CQS), Feeling of Contrast Index (FCI), Memory colour ...
Dangol, R., Rajendra Dangol, Dangol, Rajendra, Dangol, R, Bhusal, Pramod, Bhusal, P., Pramod Bhusal   +6 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Energy efficient innovative lighting and energy supply solutions in developing countries

, 2007
The vast majority of the rural population in the de veloping countries is out of reach of electricity and hence has to depend on the tradi tional fuels to fulfil the daily energy needs.
Halonen, L., Eloholma, M., Zahnd, A., Bhusal, P.   +3 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source