Results 101 to 110 of about 87,316 (308)

Daylight: What makes the difference?

, 2019
Light is necessary for vision; it enables us to sense and perceive our surroundings and in many direct and indirect ways, via eye and skin, affects our physiological and psychological health.
Aarts, M. P.J., Bueno, Bruno, Zemmouri, N, Hobday, R., Appelt, S., Zemmouri, N., Appelt, S, Norton, B, Norton, B., Stefani, Oliver, Aarts, M.P.J., Wirz-Justice, A., Bueno Unzeta, Bruno, Kantermann, Thomas, Aarts, M. P. J., Aarts, M.P.J.; id_orcid, Stefani, O., Martiny, Klaus, Aarts, MPJ, Knoop, M., Knoop, Martine, Wirz-Justice, Anne, Matusiak, B., Tandermann, T., Matusiak, Barbara Szybinska, Norton, Brian, Martiny, K., Aarts, M., Kantermann, T., Hobday, Rickard, Bueno, B.   +30 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Guide for optimizing the effectiveness and the efficiency of roadway lighting. [PDF]

Contract No. 21151The objective of the present project was to develop a simple guide for roadway lighting replacementapproaches using new light source technologies to maintain visibility for safety, while reducing energy use.Several roadway types were ...
Bullough, J. D., Rensselaer Polytechnic Institute. Lighting Research Center   +1 more
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Interfacial Chemical and Electrical Performance Study and Thermal Annealing Refinement for AlTiO/4H-SiC MOS Capacitors

Nanomaterials
The gate reliability issues in SiC-based devices with a gate dielectric formed through heat oxidation are important factors limiting their application in power devices.
Yu-Xuan Zeng, Wei Huang, Hong-Ping Ma, Qing-Chun Zhang   +3 more
doaj   +1 more source

LIGHTING TECHNOLOGY AND HUMAN

Arts and Music in Cultural Discourse. Proceedings of the International Scientific and Practical Conference, 2018
In the 20th century there was not so wide light sources choice like it is nowadays. Today it is possible to get lamps and other light sources of any colour, size, and brightness. Each of them affects people in their own way. Outside everyone can notice bright advertisments which use neon lamps and other types of lighting.
openaire   +2 more sources

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Experiment and Analysis of Termination Robustness Design for 1200 V 4H-SiC MOSFET

Nanomaterials
This study investigates the degradation mechanisms of 1200 V SiC MOSFETs during High-temperature Reverse Bias (HTRB) reliability testing, focusing on breakdown voltage (BV) reduction.
Mengyuan Yu, Yi Shen, Hongping Ma, Qingchun Zhang   +3 more
doaj   +1 more source

Subjective preference of light colour and LED lighting [PDF]

, 2015
The main objective of this work is to investigate the subjective preferences for lighting environments under different LED spectral power distributions (SPDs) and to analyse the different existing colour quality descriptors in order to recommend the best
Dangol, Rajendra
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source