Results 111 to 120 of about 87,316 (308)

Personalized office lighting for circadian health and improved sleep

, 2020
In modern society, the average person spends more than 90% of their time indoors. However, despite the growing scientific understanding of the impact of light on biological mechanisms, the existing light in the built environment is designed predominantly
Papatsimpa, Charikleia, Linnartz, Jean Paul, Charikleia Papatsimpa, Jean-Paul Linnartz, Linnartz, Jean Paul; id_orcid   +4 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Intelligent illuminance control in a dimmable LED lighting system [PDF]

, 2017
The dimmability of light-emitting diodes (LEDs) offers lighting designers great flexibility in illuminating an indoor environment. However, even for experienced lighting designers, it is not easy to achieve both comfort and energy efficiency using large ...
Linnartz, J.P.M.G., Linnartz, JPMG Jean-Paul, Linnartz, J.P.M.G.; id_orcid, Wang, X., Wang, X Xin   +4 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Technological innovation: lighting

TEPEXI Boletín Científico de la Escuela Superior Tepeji del Río, 2013
Innovation is the only way to create wealth over the medium term. One of the most important innovations of men’s history is the electrical light bulb that generates new social changes. Before electrical light bulbs, houses and streets were lighted candles elements, but they had some disadvantages.
openaire   +2 more sources

Effects of realistic office daylighting and electric lighting conditions on visual comfort, alertness and mood

Lighting conditions in workplaces contribute to a variety of factors related to work satisfaction, productivity and well-being. We tested whether different photometric variables also influence visual perception and the comfort of the lighting, as well as
Borisuit, A., Muench, M., Linhart, F., Scartezzini, J-L   +3 more
core   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Smart office lighting control using occupancy sensors

, 2017
Nowadays, despite the use of efficient LED lighting, lighting consumes a considerable amount of energy. To reduce the energy consumption, many office lighting systems are equipped with occupancy sensors.
Liotta, Antonio, Basile, Francesco, Tjalkens, T.J., Zhou, MengChu, Vasilakos, Athanasios V., Fortino, Giancarlo, Palau, Carlos, Vinci, Andrea, Fanti, Maria Pia, Lukszo, Zofia, Wang, X., Guerrieri, Antonio, Linnartz, J.-P.   +12 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Retinal phototoxicity and the evaluation of the blue light hazard of a new solid-state lighting technology. [PDF]

Sci Rep, 2020
Jaadane I, Villalpando Rodriguez G, Boulenguez P, Carré S, Dassieni I, Lebon C, Chahory S, Behar-Cohen F, Martinsons C, Torriglia A.   +9 more
europepmc   +1 more source