Results 61 to 70 of about 50,981 (256)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Acute heat stress (AHS) modifies the structure of myofibrils affecting functional properties of meat, mainly the water holding capacity. This experiment aimed to identify changes in proteolysis and migration between the myofibrillar and sarcoplasmatic ...
Carolina de Castro Santos +7 more
doaj +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Regression Approach in the Evaluation of White’s Effect Magnitude in Comparison to Lightness
In the achromatic White's grid, the grey patches between the grey lines are perceived as darker while the same elements inserted between white lines are perceived lighter than their true measured values.
Ivan Budimir +3 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Unbearable Lightness was a public artwork of 110 LED scrolling text boxes distributed throughout the canopy of a large, mature tree, located in a high traffic location in a major Brisbane Parkland.
Armstrong, Keith M.
core
Understanding Lightness and Brightness in Different Media
This thesis aimed to study how lightness and brightness perception relate to each other. We used a simple task to study whether observers perceive lightness and brightness to be different percepts and what cues they use to make these judgments.
Patel, Jaykishan Yogeshbhai
core
Termorretificação e colorimetria da madeira de Eucalyptus grandis
A termorretificação pode ser utilizada na alteração da cor da madeira, tornado-a semelhante às madeiras tropicais de maior valor agregado. O objetivo deste trabalho foi avaliar as alterações colorimétricas na madeira de Eucalyptus grandis submetida a 140,
Antônio José Vinha Zanuncio +2 more
doaj +1 more source

